Sex differences in the relationship between body composition and MASLD progression in a murine model of metabolic syndrome

Sex differences in the relationship between body composition and MASLD progression in a murine model of metabolic syndrome

Summary: Metabolic dysfunction-associated steatotic liver disease (MASLD) progression exhibits significant sex differences, with males generally developing more severe disease. This study used an endothelial nitric oxide synthase knockout (eNOS KO) murine model to investigate sex-specific MASLD prog...

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Bibliographic Details
Main Authors: Laura Manjarrés, Aline Xavier, Leticia González, Camila Garrido, Flavia C. Zacconi, Katherine Rivera, Laura Parra, Alkystis Phinikaridou, Cecilia Besa, Marcelo E. Andia
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:iScience
Subjects:
Genetics
Human metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225001233
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