The role of KLF4 in human primordial germ cell development
Primordial germ cells (PGCs) are the founder cells that develop into mature gametes. PGCs emerge during weeks 2–3 of human embryo development. Pluripotency genes are reactivated during PGC specification, including Krüppel-like factor KLF4, but its precise role in PGC development is unclear. Here, we...
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Main Authors: | Sun-Min Lee, Merrick Pierson Smela, M. Azim Surani |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2025-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/10.1098/rsob.240214 |
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