Nintedanib alleviates hyperoxia-induced lung injury via targeting NF-κB signalling pathway in rat model of bronchopulmonary dysplasia

Nintedanib alleviates hyperoxia-induced lung injury via targeting NF-κB signalling pathway in rat model of bronchopulmonary dysplasia

INTRODUCTION: Bronchopulmonary dysplasia (BPD) is a common chronic respiratory disease in premature infants. Hyperoxia is the main pathogenic factor of BPD. Nintedanib is a small-molecule tyrosine kinase inhibitor that has been confirmed to affect several cellular processes in different diseases. Th...

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Bibliographic Details
Main Authors: Rui Hao, Yuping Li, Junhui Li, Zirui Guo, Zhi Yang, Wei Lu
Format: Article
Language:English
Published: Via Medica 2025-06-01
Series:Folia Histochemica et Cytobiologica
Subjects:
newborn rats
bronchopulmonary dysplasia
NF-κB
hyperoxia
nintedanib
Online Access:https://journals.viamedica.pl/folia_histochemica_cytobiologica/article/view/105218
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