Endometrial Carcinoma Presenting as Vasculitic Sensorimotor Polyneuropathy
Paraneoplastic syndromes (PNS) are a heterogeneous group of symptoms which are indirectly caused by primary or metastatic tumor. Paraneoplastic polyneuropathy (PNP) is mostly related to small cell lung cancer (5%), prostate, gastric, and breast cancer. Only sporadic cases have been reported to be as...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2011/968756 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832555927788584960 |
|---|---|
| author | Marketa Vasku Thomas Papathemelis Nicolai Maass Ivo Meinhold-Heerlein Dirk Bauerschlag |
| author_facet | Marketa Vasku Thomas Papathemelis Nicolai Maass Ivo Meinhold-Heerlein Dirk Bauerschlag |
| author_sort | Marketa Vasku |
| collection | DOAJ |
| description | Paraneoplastic syndromes (PNS) are a heterogeneous group of symptoms which are indirectly caused by primary or metastatic tumor. Paraneoplastic polyneuropathy (PNP) is mostly related to small cell lung cancer (5%), prostate, gastric, and breast cancer. Only sporadic cases have been reported to be associated with endometrial cancer. We present a case of a premenopausal woman with severe vasculitic, asymmetric sensorimotor polyneuropathy that developed in conjunction with an endometrial carcinoma responding to surgical therapy of primary tumor combined to steroid therapy. Neurological symptoms such as asymmetrical sensorimotor deficits and painful paresthesias are suspicious when they occur in otherwise healthy women with no medical history. The phenomenon of a paraneoplastic syndrome can point to an underlying malignancy and can be used as marker of progression or regression of the tumor. Due to the rarity of PNP, there is no standard treatment. Recommended therapy is stage-adjusted treatment of the primary tumor. |
| format | Article |
| id | doaj-art-7a38f848a8f8413c9a8f50036e36612f |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-7a38f848a8f8413c9a8f50036e36612f2025-02-03T05:46:45ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922011-01-01201110.1155/2011/968756968756Endometrial Carcinoma Presenting as Vasculitic Sensorimotor PolyneuropathyMarketa Vasku0Thomas Papathemelis1Nicolai Maass2Ivo Meinhold-Heerlein3Dirk Bauerschlag4Department of Gynecology and Obstetrics, University Medical Center Aachen, Pauwelsstraße 30, 52074 Aachen, GermanyDepartment of Gynecology and Obstetrics, University Medical Center Aachen, Pauwelsstraße 30, 52074 Aachen, GermanyDepartment of Gynecology and Obstetrics, University Medical Center Aachen, Pauwelsstraße 30, 52074 Aachen, GermanyDepartment of Gynecology and Obstetrics, University Medical Center Aachen, Pauwelsstraße 30, 52074 Aachen, GermanyDepartment of Gynecology and Obstetrics, University Medical Center Aachen, Pauwelsstraße 30, 52074 Aachen, GermanyParaneoplastic syndromes (PNS) are a heterogeneous group of symptoms which are indirectly caused by primary or metastatic tumor. Paraneoplastic polyneuropathy (PNP) is mostly related to small cell lung cancer (5%), prostate, gastric, and breast cancer. Only sporadic cases have been reported to be associated with endometrial cancer. We present a case of a premenopausal woman with severe vasculitic, asymmetric sensorimotor polyneuropathy that developed in conjunction with an endometrial carcinoma responding to surgical therapy of primary tumor combined to steroid therapy. Neurological symptoms such as asymmetrical sensorimotor deficits and painful paresthesias are suspicious when they occur in otherwise healthy women with no medical history. The phenomenon of a paraneoplastic syndrome can point to an underlying malignancy and can be used as marker of progression or regression of the tumor. Due to the rarity of PNP, there is no standard treatment. Recommended therapy is stage-adjusted treatment of the primary tumor.http://dx.doi.org/10.1155/2011/968756 |
| spellingShingle | Marketa Vasku Thomas Papathemelis Nicolai Maass Ivo Meinhold-Heerlein Dirk Bauerschlag Endometrial Carcinoma Presenting as Vasculitic Sensorimotor Polyneuropathy Case Reports in Obstetrics and Gynecology |
| title | Endometrial Carcinoma Presenting as Vasculitic Sensorimotor Polyneuropathy |
| title_full | Endometrial Carcinoma Presenting as Vasculitic Sensorimotor Polyneuropathy |
| title_fullStr | Endometrial Carcinoma Presenting as Vasculitic Sensorimotor Polyneuropathy |
| title_full_unstemmed | Endometrial Carcinoma Presenting as Vasculitic Sensorimotor Polyneuropathy |
| title_short | Endometrial Carcinoma Presenting as Vasculitic Sensorimotor Polyneuropathy |
| title_sort | endometrial carcinoma presenting as vasculitic sensorimotor polyneuropathy |
| url | http://dx.doi.org/10.1155/2011/968756 |
| work_keys_str_mv | AT marketavasku endometrialcarcinomapresentingasvasculiticsensorimotorpolyneuropathy AT thomaspapathemelis endometrialcarcinomapresentingasvasculiticsensorimotorpolyneuropathy AT nicolaimaass endometrialcarcinomapresentingasvasculiticsensorimotorpolyneuropathy AT ivomeinholdheerlein endometrialcarcinomapresentingasvasculiticsensorimotorpolyneuropathy AT dirkbauerschlag endometrialcarcinomapresentingasvasculiticsensorimotorpolyneuropathy |