A Rare Case of Multiorgan Calciphylaxis in a Patient with Stage 5 Chronic Kidney Disease
Calciphylaxis or calcific uremic arteriolopathy (CUA) is a potentially life-threatening vasculopathy involving the skin and subcutaneous tissues. It is usually associated with chronic kidney disease (CKD) and rarely with acute renal failure or predialysis patients. The clinical diagnosis of calcific...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2018/9603680 |
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| author | Abdulrahman Ahmad Ali Albaghli Adel Michael Khaled Refaat Mohammad Omar Ahmad Ibrahim Bahaa Elmenshawy Ashraf Maher Rasha Alramah Sami Mikhail Mustafa Almahmid Husain Alenezi Yahya Elshebiney |
| author_facet | Abdulrahman Ahmad Ali Albaghli Adel Michael Khaled Refaat Mohammad Omar Ahmad Ibrahim Bahaa Elmenshawy Ashraf Maher Rasha Alramah Sami Mikhail Mustafa Almahmid Husain Alenezi Yahya Elshebiney |
| author_sort | Abdulrahman Ahmad |
| collection | DOAJ |
| description | Calciphylaxis or calcific uremic arteriolopathy (CUA) is a potentially life-threatening vasculopathy involving the skin and subcutaneous tissues. It is usually associated with chronic kidney disease (CKD) and rarely with acute renal failure or predialysis patients. The clinical diagnosis of calcific uremic arteriolopathy relies on high index of suspicion. CUA is commonly associated with secondary hyperparathyroidism and high serum calcium and phosphate products. Moreover, using biopsy as a diagnostic tool is controversial, due to the high risk of poor wound healing and sepsis. Radiological studies usually reveal extensive calcification of branching vessels such as penile arteries, eventually leading to gangrene formation in extremities and penis. Histopathological analysis confirms the diagnosis of calcific uremic arteriolopathy and rules out the presence of malignancy. CUA is a systematic disease that involves multiple organs, and to the best of our knowledge this is the first reported case involving the penis, bladder, and eyes. |
| format | Article |
| id | doaj-art-79f065ec998f40f69a9376c821650216 |
| institution | Kabale University |
| issn | 2090-696X 2090-6978 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Urology |
| spelling | doaj-art-79f065ec998f40f69a9376c8216502162025-02-03T05:57:35ZengWileyCase Reports in Urology2090-696X2090-69782018-01-01201810.1155/2018/96036809603680A Rare Case of Multiorgan Calciphylaxis in a Patient with Stage 5 Chronic Kidney DiseaseAbdulrahman Ahmad0Ali Albaghli1Adel Michael2Khaled Refaat3Mohammad Omar4Ahmad Ibrahim5Bahaa Elmenshawy6Ashraf Maher7Rasha Alramah8Sami Mikhail9Mustafa Almahmid10Husain Alenezi11Yahya Elshebiney12Department of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitDepartment of Urology, Aladan Hospital, KuwaitCalciphylaxis or calcific uremic arteriolopathy (CUA) is a potentially life-threatening vasculopathy involving the skin and subcutaneous tissues. It is usually associated with chronic kidney disease (CKD) and rarely with acute renal failure or predialysis patients. The clinical diagnosis of calcific uremic arteriolopathy relies on high index of suspicion. CUA is commonly associated with secondary hyperparathyroidism and high serum calcium and phosphate products. Moreover, using biopsy as a diagnostic tool is controversial, due to the high risk of poor wound healing and sepsis. Radiological studies usually reveal extensive calcification of branching vessels such as penile arteries, eventually leading to gangrene formation in extremities and penis. Histopathological analysis confirms the diagnosis of calcific uremic arteriolopathy and rules out the presence of malignancy. CUA is a systematic disease that involves multiple organs, and to the best of our knowledge this is the first reported case involving the penis, bladder, and eyes.http://dx.doi.org/10.1155/2018/9603680 |
| spellingShingle | Abdulrahman Ahmad Ali Albaghli Adel Michael Khaled Refaat Mohammad Omar Ahmad Ibrahim Bahaa Elmenshawy Ashraf Maher Rasha Alramah Sami Mikhail Mustafa Almahmid Husain Alenezi Yahya Elshebiney A Rare Case of Multiorgan Calciphylaxis in a Patient with Stage 5 Chronic Kidney Disease Case Reports in Urology |
| title | A Rare Case of Multiorgan Calciphylaxis in a Patient with Stage 5 Chronic Kidney Disease |
| title_full | A Rare Case of Multiorgan Calciphylaxis in a Patient with Stage 5 Chronic Kidney Disease |
| title_fullStr | A Rare Case of Multiorgan Calciphylaxis in a Patient with Stage 5 Chronic Kidney Disease |
| title_full_unstemmed | A Rare Case of Multiorgan Calciphylaxis in a Patient with Stage 5 Chronic Kidney Disease |
| title_short | A Rare Case of Multiorgan Calciphylaxis in a Patient with Stage 5 Chronic Kidney Disease |
| title_sort | rare case of multiorgan calciphylaxis in a patient with stage 5 chronic kidney disease |
| url | http://dx.doi.org/10.1155/2018/9603680 |
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