Primary Intimal (Spindle Cell) Sarcoma of the Heart: A Case Report and Review of the Literature

Intimal (spindle cell) sarcomas of the left atrium are extremely rare primary cardiac tumours with three cases reported (Li et al. (2013), Cho et al. (2006), and Modi et al. (2009)). We present a 69-year-old man who first came to medical attention after experiencing abdominal discomfort. He had a 30...

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Main Authors: A. Ibrahim, A. Luk, P. Singhal, Bo Wan, A. Zavodni, R. J. Cusimano, J. Butany
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/461815
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author A. Ibrahim
A. Luk
P. Singhal
Bo Wan
A. Zavodni
R. J. Cusimano
J. Butany
author_facet A. Ibrahim
A. Luk
P. Singhal
Bo Wan
A. Zavodni
R. J. Cusimano
J. Butany
author_sort A. Ibrahim
collection DOAJ
description Intimal (spindle cell) sarcomas of the left atrium are extremely rare primary cardiac tumours with three cases reported (Li et al. (2013), Cho et al. (2006), and Modi et al. (2009)). We present a 69-year-old man who first came to medical attention after experiencing abdominal discomfort. He had a 30 lb weight loss apparently due to dieting. He denied any other constitutional symptoms. His symptoms persisted despite a course of antibiotics for presumed diverticulitis. Laboratory values were within normal limits, though the haemoglobin was 131 g/L (normal: 140–180). Subsequent abdominal computed tomography (CT) scan revealed an abdominal wall mass and intracardiac lesion; the cardiac mass was further characterized by transesophageal echo (TEE), magnetic resonance imaging (MRI), and dedicated cardiac CT. TEE revealed a mass attached to the posterolateral wall of the left atrium above the mitral annulus, and the cardiac CT and MRI confirmed the TEE findings. The patient underwent extensive surgical resection and repair of the left side of the heart. Postoperatively, he developed acute renal failure requiring dialysis and reintubation for volume overload. He became acutely hypotensive, developed multiorgan failure, and succumbed to his illness. Histopathologic examination of the left atrial mass showed an intimal sarcoma.
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spelling doaj-art-79eef64f17e34f91a040e341dc3381912025-02-03T01:28:40ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/461815461815Primary Intimal (Spindle Cell) Sarcoma of the Heart: A Case Report and Review of the LiteratureA. Ibrahim0A. Luk1P. Singhal2Bo Wan3A. Zavodni4R. J. Cusimano5J. Butany6Department of Pathology, Toronto General Hospital, University Health Network, Toronto, ON, M5G 2C4, CanadaDivision of Cardiology, University of Toronto, Toronto, ON, M5T 2S8, CanadaDepartment of Pathology, Toronto General Hospital, University Health Network, Toronto, ON, M5G 2C4, CanadaDepartment of Pathology, Toronto General Hospital, University Health Network, Toronto, ON, M5G 2C4, CanadaDepartment of Radiology, Sunnybrook Hospital and University Health Network, North York, ON, M4N 3M5, CanadaDivision of Cardiac Surgery, Peter Munk Cardiac Centre, Toronto General Hospital, Toronto, ON, M5G 2C4, CanadaDepartment of Pathology, Toronto General Hospital, University Health Network, Toronto, ON, M5G 2C4, CanadaIntimal (spindle cell) sarcomas of the left atrium are extremely rare primary cardiac tumours with three cases reported (Li et al. (2013), Cho et al. (2006), and Modi et al. (2009)). We present a 69-year-old man who first came to medical attention after experiencing abdominal discomfort. He had a 30 lb weight loss apparently due to dieting. He denied any other constitutional symptoms. His symptoms persisted despite a course of antibiotics for presumed diverticulitis. Laboratory values were within normal limits, though the haemoglobin was 131 g/L (normal: 140–180). Subsequent abdominal computed tomography (CT) scan revealed an abdominal wall mass and intracardiac lesion; the cardiac mass was further characterized by transesophageal echo (TEE), magnetic resonance imaging (MRI), and dedicated cardiac CT. TEE revealed a mass attached to the posterolateral wall of the left atrium above the mitral annulus, and the cardiac CT and MRI confirmed the TEE findings. The patient underwent extensive surgical resection and repair of the left side of the heart. Postoperatively, he developed acute renal failure requiring dialysis and reintubation for volume overload. He became acutely hypotensive, developed multiorgan failure, and succumbed to his illness. Histopathologic examination of the left atrial mass showed an intimal sarcoma.http://dx.doi.org/10.1155/2013/461815
spellingShingle A. Ibrahim
A. Luk
P. Singhal
Bo Wan
A. Zavodni
R. J. Cusimano
J. Butany
Primary Intimal (Spindle Cell) Sarcoma of the Heart: A Case Report and Review of the Literature
Case Reports in Medicine
title Primary Intimal (Spindle Cell) Sarcoma of the Heart: A Case Report and Review of the Literature
title_full Primary Intimal (Spindle Cell) Sarcoma of the Heart: A Case Report and Review of the Literature
title_fullStr Primary Intimal (Spindle Cell) Sarcoma of the Heart: A Case Report and Review of the Literature
title_full_unstemmed Primary Intimal (Spindle Cell) Sarcoma of the Heart: A Case Report and Review of the Literature
title_short Primary Intimal (Spindle Cell) Sarcoma of the Heart: A Case Report and Review of the Literature
title_sort primary intimal spindle cell sarcoma of the heart a case report and review of the literature
url http://dx.doi.org/10.1155/2013/461815
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