Eicosapentaenoic Acid Improves Endothelial Nitric Oxide Bioavailability Via Changes in Protein Expression During Inflammation

Eicosapentaenoic Acid Improves Endothelial Nitric Oxide Bioavailability Via Changes in Protein Expression During Inflammation

Background Endothelial cell (EC) dysfunction involves reduced nitric oxide (NO) bioavailability due to NO synthase uncoupling linked to increased oxidation and reduced cofactor availability. Loss of endothelial function and NO bioavailability are associated with inflammation, including leukocyte act...

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Bibliographic Details
Main Authors: Samuel C. R. Sherratt, Peter Libby, Hazem Dawoud, Deepak L. Bhatt, R. Preston Mason
Format: Article
Language:English
Published: Wiley 2024-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
eicosapentaenoic acid
endothelial function
nitric oxide
proteomics
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.034076
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