Alteration in gut microbiota after colonoscopy: proposed mechanisms and the role of probiotic interventions
Colonoscopy, a widely used procedure for diagnosing and treating colonic diseases, induces transient gastrointestinal symptoms and alterations in the gut microbiota. This review comprehensively examines the evidence on alterations in the gut microbiota following colonoscopy and their possible mechan...
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| Format: | Article |
| Language: | English |
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Korean Society of Gastrointestinal Endoscopy
2025-01-01
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| Series: | Clinical Endoscopy |
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| Online Access: | http://www.e-ce.org/upload/pdf/ce-2024-147.pdf |
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| _version_ | 1832545173434793984 |
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| author | Hyeong Ho Jo Moon Young Lee Se Eun Ha Dong Han Yeom Yong Sung Kim |
| author_facet | Hyeong Ho Jo Moon Young Lee Se Eun Ha Dong Han Yeom Yong Sung Kim |
| author_sort | Hyeong Ho Jo |
| collection | DOAJ |
| description | Colonoscopy, a widely used procedure for diagnosing and treating colonic diseases, induces transient gastrointestinal symptoms and alterations in the gut microbiota. This review comprehensively examines the evidence on alterations in the gut microbiota following colonoscopy and their possible mechanisms. Factors such as rapid colonic evacuation, increased osmolality, and mucus thinning caused by bowel preparation and exposure to oxygen during the procedure contribute to these alterations. Typically, the alterations revert to the baseline within a short time. However, their long-term implications remain unclear, necessitating further investigation. Split-dose bowel preparation and CO2 insufflation during the procedure result in fewer alterations in the gut microbiota. Probiotic administration immediately after colonoscopy shows promise in reducing alterations and gastrointestinal symptoms. However, the widespread use of probiotics remains controversial due to the transient nature of both the symptoms and gut microbial alterations following a colonoscopy. Probiotics may offer greater benefits to individuals with preexisting gastrointestinal symptoms. Thus, probiotic administration may be a viable option for selected patients. |
| format | Article |
| id | doaj-art-79b3f8b07805493d9577ac815a005507 |
| institution | Kabale University |
| issn | 2234-2400 2234-2443 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Korean Society of Gastrointestinal Endoscopy |
| record_format | Article |
| series | Clinical Endoscopy |
| spelling | doaj-art-79b3f8b07805493d9577ac815a0055072025-02-03T08:08:03ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432025-01-01581253910.5946/ce.2024.1477938Alteration in gut microbiota after colonoscopy: proposed mechanisms and the role of probiotic interventionsHyeong Ho Jo0Moon Young Lee1Se Eun Ha2Dong Han Yeom3Yong Sung Kim4 Department of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea Digestive Disease Research Institute, Wonkwang University College of Medicine, Iksan, Korea Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV, USA Department of Gastroenterology, Wonkwang University School of Medicine, Iksan, Korea Digestive Disease Research Institute, Wonkwang University College of Medicine, Iksan, KoreaColonoscopy, a widely used procedure for diagnosing and treating colonic diseases, induces transient gastrointestinal symptoms and alterations in the gut microbiota. This review comprehensively examines the evidence on alterations in the gut microbiota following colonoscopy and their possible mechanisms. Factors such as rapid colonic evacuation, increased osmolality, and mucus thinning caused by bowel preparation and exposure to oxygen during the procedure contribute to these alterations. Typically, the alterations revert to the baseline within a short time. However, their long-term implications remain unclear, necessitating further investigation. Split-dose bowel preparation and CO2 insufflation during the procedure result in fewer alterations in the gut microbiota. Probiotic administration immediately after colonoscopy shows promise in reducing alterations and gastrointestinal symptoms. However, the widespread use of probiotics remains controversial due to the transient nature of both the symptoms and gut microbial alterations following a colonoscopy. Probiotics may offer greater benefits to individuals with preexisting gastrointestinal symptoms. Thus, probiotic administration may be a viable option for selected patients.http://www.e-ce.org/upload/pdf/ce-2024-147.pdfcolonoscopydysbiosismicrobiotaprobiotics |
| spellingShingle | Hyeong Ho Jo Moon Young Lee Se Eun Ha Dong Han Yeom Yong Sung Kim Alteration in gut microbiota after colonoscopy: proposed mechanisms and the role of probiotic interventions Clinical Endoscopy colonoscopy dysbiosis microbiota probiotics |
| title | Alteration in gut microbiota after colonoscopy: proposed mechanisms and the role of probiotic interventions |
| title_full | Alteration in gut microbiota after colonoscopy: proposed mechanisms and the role of probiotic interventions |
| title_fullStr | Alteration in gut microbiota after colonoscopy: proposed mechanisms and the role of probiotic interventions |
| title_full_unstemmed | Alteration in gut microbiota after colonoscopy: proposed mechanisms and the role of probiotic interventions |
| title_short | Alteration in gut microbiota after colonoscopy: proposed mechanisms and the role of probiotic interventions |
| title_sort | alteration in gut microbiota after colonoscopy proposed mechanisms and the role of probiotic interventions |
| topic | colonoscopy dysbiosis microbiota probiotics |
| url | http://www.e-ce.org/upload/pdf/ce-2024-147.pdf |
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