Long‐Circulating Nanobody Confers Durable Prophylaxis against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Infection

Long‐Circulating Nanobody Confers Durable Prophylaxis against Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Infection

Breakthrough infections in vaccinated population and continuous emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants make it imperative to develop more efficacious medical countermeasures. Previously, an anti‐SARS‐CoV‐2 nanobody, Nanosota‐3A, that neutralizes the infect...

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Bibliographic Details
Main Authors: Geetha Jyothi Vaskuri, Gang Ye, Fan Bu, Dong Yang, Colleen B. Jonsson, Hailey Turner‐Hubbard, Sydney Winecke, Alise Mendoza, Fang Li, Chalet Tan
Format: Article
Language:English
Published: Wiley-VCH 2025-08-01
Series:Advanced NanoBiomed Research
Subjects:
Fc engineering
FcRn
half‐life extension
nanobody
pharmacokinetics
pre‐exposure prophylaxis
Online Access:https://doi.org/10.1002/anbr.202400214
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