Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil
Chagas disease in patients with HIV infection represents a potentially serious event with high case fatality rates. This study describes epidemiological and clinical aspects of deaths related to Chagas disease and HIV/AIDS coinfection in Brazil, 1999–2007. We performed a descriptive study based on m...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/534649 |
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| author | Francisco Rogerlândio Martins-Melo Alberto Novaes Ramos Carlos Henrique Alencar Jorg Heukelbach |
| author_facet | Francisco Rogerlândio Martins-Melo Alberto Novaes Ramos Carlos Henrique Alencar Jorg Heukelbach |
| author_sort | Francisco Rogerlândio Martins-Melo |
| collection | DOAJ |
| description | Chagas disease in patients with HIV infection represents a potentially serious event with high case fatality rates. This study describes epidemiological and clinical aspects of deaths related to Chagas disease and HIV/AIDS coinfection in Brazil, 1999–2007. We performed a descriptive study based on mortality data from the nationwide Mortality Information System. Of a total of about 9 million deaths, Chagas disease and HIV/AIDS were mentioned in the same death certificate in 74 cases. AIDS was an underlying cause in 77.0% (57) and Chagas disease in 17.6% (13). Males (51.4%), white skin color (50%), age group 40–49 years (29.7%), and residents in the Southeast region (75.7%) were most common. Mean age at death was significantly lower in the coinfected (47.1 years [SD ± 14.6]), as compared to Chagas disease deaths (64.1 years [SD ± 14.7], P<0.001). Considering the lack of data on morbidity related to Chagas disease and AIDS coinfection, the use of mortality data may be an appropriate sentinel approach to monitor the occurrence of this association. Due to the epidemiological transition in Brazil, chronic Chagas disease and HIV/AIDS coinfection will be further complicated and require the development of evidence-based preventive control measures. |
| format | Article |
| id | doaj-art-79a56ba7be8f4939bbf34777c92bb776 |
| institution | Kabale University |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-79a56ba7be8f4939bbf34777c92bb7762025-02-03T01:27:53ZengWileyJournal of Tropical Medicine1687-96861687-96942012-01-01201210.1155/2012/534649534649Mortality Related to Chagas Disease and HIV/AIDS Coinfection in BrazilFrancisco Rogerlândio Martins-Melo0Alberto Novaes Ramos1Carlos Henrique Alencar2Jorg Heukelbach3Department of Community Health, School of Medicine, Federal University of Ceará, 60430-140 Fortaleza, CE, BrazilDepartment of Community Health, School of Medicine, Federal University of Ceará, 60430-140 Fortaleza, CE, BrazilDepartment of Community Health, School of Medicine, Federal University of Ceará, 60430-140 Fortaleza, CE, BrazilDepartment of Community Health, School of Medicine, Federal University of Ceará, 60430-140 Fortaleza, CE, BrazilChagas disease in patients with HIV infection represents a potentially serious event with high case fatality rates. This study describes epidemiological and clinical aspects of deaths related to Chagas disease and HIV/AIDS coinfection in Brazil, 1999–2007. We performed a descriptive study based on mortality data from the nationwide Mortality Information System. Of a total of about 9 million deaths, Chagas disease and HIV/AIDS were mentioned in the same death certificate in 74 cases. AIDS was an underlying cause in 77.0% (57) and Chagas disease in 17.6% (13). Males (51.4%), white skin color (50%), age group 40–49 years (29.7%), and residents in the Southeast region (75.7%) were most common. Mean age at death was significantly lower in the coinfected (47.1 years [SD ± 14.6]), as compared to Chagas disease deaths (64.1 years [SD ± 14.7], P<0.001). Considering the lack of data on morbidity related to Chagas disease and AIDS coinfection, the use of mortality data may be an appropriate sentinel approach to monitor the occurrence of this association. Due to the epidemiological transition in Brazil, chronic Chagas disease and HIV/AIDS coinfection will be further complicated and require the development of evidence-based preventive control measures.http://dx.doi.org/10.1155/2012/534649 |
| spellingShingle | Francisco Rogerlândio Martins-Melo Alberto Novaes Ramos Carlos Henrique Alencar Jorg Heukelbach Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil Journal of Tropical Medicine |
| title | Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil |
| title_full | Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil |
| title_fullStr | Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil |
| title_full_unstemmed | Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil |
| title_short | Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil |
| title_sort | mortality related to chagas disease and hiv aids coinfection in brazil |
| url | http://dx.doi.org/10.1155/2012/534649 |
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