Clinical Characteristics and Outcomes of Acute Myeloid Leukemia Patients Harboring Triple Mutations and the Potential Prognostic Value of

Clinical Characteristics and Outcomes of Acute Myeloid Leukemia Patients Harboring Triple Mutations and the Potential Prognostic Value of

Introduction Nucleophosmin 1 ( NPM1 ), FMS-like tyrosine kinase 3-internal tandem duplication ( FLT3-ITD ), and de novo methyl transferase 3 A ( DNMT3A ) triple-mutated acute myeloid leukemia (AML) represents a distinct entity with poor outcomes. Methods We explored the gene mutation spectrum and cl...

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Main Authors: Yujie Niu MD, Xingchun Luo MD, Xiaoxiao Yang MD, Yuancheng Guo MD, Xiao Tang MD, Long Zhao MD, Jinli Jian MD, Bei Liu MD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2025-07-01
Series:Cancer Control
Online Access:https://doi.org/10.1177/10732748251359836
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