Synthesis and Studies of Novel Optically Active Schiff’s Base Derivatives and their Antimicrobial Activities

Several new Schiff’s base derivatives were prepared by condensing various substituted benzaldehyde with 1-(4-aminophenyl)-2-{4-[(S)-(4-chlorophenyl)(phenyl) methyl]-1-piperazinyl}ethanone in presence of acid catalyst under reflux condition. All the compounds were characterized by elemental analysis...

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Main Authors: Ishwar J. Patel, Shailesh J. Parmar
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2010/956242
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author Ishwar J. Patel
Shailesh J. Parmar
author_facet Ishwar J. Patel
Shailesh J. Parmar
author_sort Ishwar J. Patel
collection DOAJ
description Several new Schiff’s base derivatives were prepared by condensing various substituted benzaldehyde with 1-(4-aminophenyl)-2-{4-[(S)-(4-chlorophenyl)(phenyl) methyl]-1-piperazinyl}ethanone in presence of acid catalyst under reflux condition. All the compounds were characterized by elemental analysis and spectral studies. The newly synthesized compounds were evaluated for their antibacterial and antifungal activity.
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institution Kabale University
issn 0973-4945
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spelling doaj-art-78f6cdae40b944eea48bd467881074be2025-02-03T05:53:58ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017261762310.1155/2010/956242Synthesis and Studies of Novel Optically Active Schiff’s Base Derivatives and their Antimicrobial ActivitiesIshwar J. Patel0Shailesh J. Parmar1Department of Chemistry, SIR. P. T. Sarvajanik College of Science, Veer Narmad South Gujarat University, Surat 395017, Gujarat, IndiaDepartment of Chemistry, SIR. P. T. Sarvajanik College of Science, Veer Narmad South Gujarat University, Surat 395017, Gujarat, IndiaSeveral new Schiff’s base derivatives were prepared by condensing various substituted benzaldehyde with 1-(4-aminophenyl)-2-{4-[(S)-(4-chlorophenyl)(phenyl) methyl]-1-piperazinyl}ethanone in presence of acid catalyst under reflux condition. All the compounds were characterized by elemental analysis and spectral studies. The newly synthesized compounds were evaluated for their antibacterial and antifungal activity.http://dx.doi.org/10.1155/2010/956242
spellingShingle Ishwar J. Patel
Shailesh J. Parmar
Synthesis and Studies of Novel Optically Active Schiff’s Base Derivatives and their Antimicrobial Activities
E-Journal of Chemistry
title Synthesis and Studies of Novel Optically Active Schiff’s Base Derivatives and their Antimicrobial Activities
title_full Synthesis and Studies of Novel Optically Active Schiff’s Base Derivatives and their Antimicrobial Activities
title_fullStr Synthesis and Studies of Novel Optically Active Schiff’s Base Derivatives and their Antimicrobial Activities
title_full_unstemmed Synthesis and Studies of Novel Optically Active Schiff’s Base Derivatives and their Antimicrobial Activities
title_short Synthesis and Studies of Novel Optically Active Schiff’s Base Derivatives and their Antimicrobial Activities
title_sort synthesis and studies of novel optically active schiff s base derivatives and their antimicrobial activities
url http://dx.doi.org/10.1155/2010/956242
work_keys_str_mv AT ishwarjpatel synthesisandstudiesofnovelopticallyactiveschiffsbasederivativesandtheirantimicrobialactivities
AT shaileshjparmar synthesisandstudiesofnovelopticallyactiveschiffsbasederivativesandtheirantimicrobialactivities