Neoantigen immunotherapy: a novel treatment for bladder cancer

Bladder cancer is currently the most common malignant tumor of the urinary system. The traditional treatment methods for bladder cancer are mainly surgery, chemotherapy, radiotherapy, and targeted therapy; however, these treatment methods do not improve the clinical prognosis of patients with advanc...

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Main Authors: Ruiyang Lv, Zhenzhu Liu, Maoxin Lv, Yuze Song, Junlin Wang, Huizhi Mu, Yu Zhang, Xuejian Wang
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2025-01-01
Series:Exploration of Targeted Anti-tumor Therapy
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Online Access:https://www.explorationpub.com/uploads/Article/A1002288/1002288.pdf
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author Ruiyang Lv
Zhenzhu Liu
Maoxin Lv
Yuze Song
Junlin Wang
Huizhi Mu
Yu Zhang
Xuejian Wang
author_facet Ruiyang Lv
Zhenzhu Liu
Maoxin Lv
Yuze Song
Junlin Wang
Huizhi Mu
Yu Zhang
Xuejian Wang
author_sort Ruiyang Lv
collection DOAJ
description Bladder cancer is currently the most common malignant tumor of the urinary system. The traditional treatment methods for bladder cancer are mainly surgery, chemotherapy, radiotherapy, and targeted therapy; however, these treatment methods do not improve the clinical prognosis of patients with advanced or metastatic bladder cancer. Consequently, there is an urgent need to develop new treatment methods to improve the survival rate and quality-of-life of patients with bladder cancer. Over recent years, the rapid development of tumor immunotherapy has become a significant alternative to traditional treatment, and provides new hope to patients. This review aims to introduce neoantigens and their possible role in the treatment of bladder cancer, and to explore the current limitations of neoantigens for the treatment of bladder cancer.
format Article
id doaj-art-78f1068fc7cb4f839885515be7150967
institution Kabale University
issn 2692-3114
language English
publishDate 2025-01-01
publisher Open Exploration Publishing Inc.
record_format Article
series Exploration of Targeted Anti-tumor Therapy
spelling doaj-art-78f1068fc7cb4f839885515be71509672025-01-26T08:32:27ZengOpen Exploration Publishing Inc.Exploration of Targeted Anti-tumor Therapy2692-31142025-01-016100228810.37349/etat.2025.1002288Neoantigen immunotherapy: a novel treatment for bladder cancerRuiyang Lv0Zhenzhu Liu1Maoxin Lv2Yuze Song3Junlin Wang4Huizhi Mu5Yu Zhang6Xuejian Wang7Department of Urology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province 116021, ChinaDepartment of Cardiovascular, Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province 116027, ChinaDepartment of Urology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province 650032, ChinaDepartment of Nursing, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province 116021, ChinaDepartment of Urology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province 116021, ChinaDepartment of Urology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province 116021, ChinaDepartment of Anesthesiology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province 116021, ChinaDepartment of Urology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province 116021, ChinaBladder cancer is currently the most common malignant tumor of the urinary system. The traditional treatment methods for bladder cancer are mainly surgery, chemotherapy, radiotherapy, and targeted therapy; however, these treatment methods do not improve the clinical prognosis of patients with advanced or metastatic bladder cancer. Consequently, there is an urgent need to develop new treatment methods to improve the survival rate and quality-of-life of patients with bladder cancer. Over recent years, the rapid development of tumor immunotherapy has become a significant alternative to traditional treatment, and provides new hope to patients. This review aims to introduce neoantigens and their possible role in the treatment of bladder cancer, and to explore the current limitations of neoantigens for the treatment of bladder cancer.https://www.explorationpub.com/uploads/Article/A1002288/1002288.pdfbladder cancerimmunotherapyneoantigens
spellingShingle Ruiyang Lv
Zhenzhu Liu
Maoxin Lv
Yuze Song
Junlin Wang
Huizhi Mu
Yu Zhang
Xuejian Wang
Neoantigen immunotherapy: a novel treatment for bladder cancer
Exploration of Targeted Anti-tumor Therapy
bladder cancer
immunotherapy
neoantigens
title Neoantigen immunotherapy: a novel treatment for bladder cancer
title_full Neoantigen immunotherapy: a novel treatment for bladder cancer
title_fullStr Neoantigen immunotherapy: a novel treatment for bladder cancer
title_full_unstemmed Neoantigen immunotherapy: a novel treatment for bladder cancer
title_short Neoantigen immunotherapy: a novel treatment for bladder cancer
title_sort neoantigen immunotherapy a novel treatment for bladder cancer
topic bladder cancer
immunotherapy
neoantigens
url https://www.explorationpub.com/uploads/Article/A1002288/1002288.pdf
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AT yuzesong neoantigenimmunotherapyanoveltreatmentforbladdercancer
AT junlinwang neoantigenimmunotherapyanoveltreatmentforbladdercancer
AT huizhimu neoantigenimmunotherapyanoveltreatmentforbladdercancer
AT yuzhang neoantigenimmunotherapyanoveltreatmentforbladdercancer
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