Ultrasound Assessment of Carotid Intima-Media Thickness: Comparison between Diabetes and Nondiabetes Subjects, and Correlation with Serum Vitamin D
Background and Objective. Diabetes contributes to considerable morbidity and mortality through vascular complications. Sonographic evaluation of carotid intima-media thickness (CIMT) is accepted as a surrogate marker for atherosclerosis. The aim of this study was to find out the difference in the CI...
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Wiley
2024-01-01
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| Series: | Radiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2024/7178920 |
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| author | Sameeah Abdulrahman Rashid |
| author_facet | Sameeah Abdulrahman Rashid |
| author_sort | Sameeah Abdulrahman Rashid |
| collection | DOAJ |
| description | Background and Objective. Diabetes contributes to considerable morbidity and mortality through vascular complications. Sonographic evaluation of carotid intima-media thickness (CIMT) is accepted as a surrogate marker for atherosclerosis. The aim of this study was to find out the difference in the CIMT between diabetes and nondiabetes and determine its correlation with serum vitamin D and some other modifiable and nonmodifiable cardiovascular risk factors. Methods. This multicenter cross-sectional study was performed on two groups of adults (nondiabetes and type 2 diabetes) of various ages, sexes, and body mass index (BMI). CIMT for each side was measured at three segments using high-resolution ultrasound, and the mean of both sides was determined. Comparison was made between each group, and the association of CIMT with each of age, sex, BMI, serum vitamin D status, smoking, and physical activity status was studied. The chi-square test was used to compare categorical data, and binary logistic regression was utilized to ascertain the relationship between CIMT and the study variables. Results. A significant difference was observed between the CIMT of the diabetes and nondiabetes group, average CIMT was 0.82 ± 0.23 mm vs. 1.12 ± 0.24 mm for the nondiabetes and diabetes group, respectively, with P value <0.005. No significant correlation was observed between serum vitamin D level and CIMT neither in the study group as a whole nor in either subgroup; however, a significant association was observed between CIMT with each of age, sex, BMI, smoking, and physical activity status. Conclusion. Ultrasound is a sensitive tool for CIMT evaluation. Diabetes has a 5.4-fold higher risk of having high CIMT. Serum vitamin D level showed no significant influence on CIMT. Smoking, BMI, and physical activity are among the modifiable risk factors with significant influence on CIMT. |
| format | Article |
| id | doaj-art-78d5b84a0bb64c3ea24967acba88d9c2 |
| institution | Kabale University |
| issn | 2090-195X |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Radiology Research and Practice |
| spelling | doaj-art-78d5b84a0bb64c3ea24967acba88d9c22025-02-03T07:23:24ZengWileyRadiology Research and Practice2090-195X2024-01-01202410.1155/2024/7178920Ultrasound Assessment of Carotid Intima-Media Thickness: Comparison between Diabetes and Nondiabetes Subjects, and Correlation with Serum Vitamin DSameeah Abdulrahman Rashid0Department of SurgeryBackground and Objective. Diabetes contributes to considerable morbidity and mortality through vascular complications. Sonographic evaluation of carotid intima-media thickness (CIMT) is accepted as a surrogate marker for atherosclerosis. The aim of this study was to find out the difference in the CIMT between diabetes and nondiabetes and determine its correlation with serum vitamin D and some other modifiable and nonmodifiable cardiovascular risk factors. Methods. This multicenter cross-sectional study was performed on two groups of adults (nondiabetes and type 2 diabetes) of various ages, sexes, and body mass index (BMI). CIMT for each side was measured at three segments using high-resolution ultrasound, and the mean of both sides was determined. Comparison was made between each group, and the association of CIMT with each of age, sex, BMI, serum vitamin D status, smoking, and physical activity status was studied. The chi-square test was used to compare categorical data, and binary logistic regression was utilized to ascertain the relationship between CIMT and the study variables. Results. A significant difference was observed between the CIMT of the diabetes and nondiabetes group, average CIMT was 0.82 ± 0.23 mm vs. 1.12 ± 0.24 mm for the nondiabetes and diabetes group, respectively, with P value <0.005. No significant correlation was observed between serum vitamin D level and CIMT neither in the study group as a whole nor in either subgroup; however, a significant association was observed between CIMT with each of age, sex, BMI, smoking, and physical activity status. Conclusion. Ultrasound is a sensitive tool for CIMT evaluation. Diabetes has a 5.4-fold higher risk of having high CIMT. Serum vitamin D level showed no significant influence on CIMT. Smoking, BMI, and physical activity are among the modifiable risk factors with significant influence on CIMT.http://dx.doi.org/10.1155/2024/7178920 |
| spellingShingle | Sameeah Abdulrahman Rashid Ultrasound Assessment of Carotid Intima-Media Thickness: Comparison between Diabetes and Nondiabetes Subjects, and Correlation with Serum Vitamin D Radiology Research and Practice |
| title | Ultrasound Assessment of Carotid Intima-Media Thickness: Comparison between Diabetes and Nondiabetes Subjects, and Correlation with Serum Vitamin D |
| title_full | Ultrasound Assessment of Carotid Intima-Media Thickness: Comparison between Diabetes and Nondiabetes Subjects, and Correlation with Serum Vitamin D |
| title_fullStr | Ultrasound Assessment of Carotid Intima-Media Thickness: Comparison between Diabetes and Nondiabetes Subjects, and Correlation with Serum Vitamin D |
| title_full_unstemmed | Ultrasound Assessment of Carotid Intima-Media Thickness: Comparison between Diabetes and Nondiabetes Subjects, and Correlation with Serum Vitamin D |
| title_short | Ultrasound Assessment of Carotid Intima-Media Thickness: Comparison between Diabetes and Nondiabetes Subjects, and Correlation with Serum Vitamin D |
| title_sort | ultrasound assessment of carotid intima media thickness comparison between diabetes and nondiabetes subjects and correlation with serum vitamin d |
| url | http://dx.doi.org/10.1155/2024/7178920 |
| work_keys_str_mv | AT sameeahabdulrahmanrashid ultrasoundassessmentofcarotidintimamediathicknesscomparisonbetweendiabetesandnondiabetessubjectsandcorrelationwithserumvitamind |