Life-threatening Pneumocystis jiroveci Pneumonia with Cytomegalovirus Coinfection in a Follicular Lymphoma Patient During Rituximab-based Chemotherapy
In the era of target therapy, we face the challenge of the risk of opportunistic infection in patients with B-cell lymphoma who receiving rituximab-based chemotherapy. Opportunistic infections such as Pneumocystis jiroveci pneumonia (PJP) and Cytomegalovirus (CMV) pneumonia are life-threatening dise...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-01-01
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| Series: | Journal of Cancer Research and Practice |
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| Online Access: | https://journals.lww.com/10.4103/ejcrp.eJCRP-D-23-00015 |
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| author | Mu-Chun Yang Sheng-Kang Chiu Jong-Kai Hsiao Woei-Yau Kao |
| author_facet | Mu-Chun Yang Sheng-Kang Chiu Jong-Kai Hsiao Woei-Yau Kao |
| author_sort | Mu-Chun Yang |
| collection | DOAJ |
| description | In the era of target therapy, we face the challenge of the risk of opportunistic infection in patients with B-cell lymphoma who receiving rituximab-based chemotherapy. Opportunistic infections such as Pneumocystis jiroveci pneumonia (PJP) and Cytomegalovirus (CMV) pneumonia are life-threatening diseases. However, PJP with CMV coinfection is rare. Here, we report a follicular lymphoma patient who suffered from PJP with CMV coinfection after receiving three cycles of rituximab, cyclophosphamide, vincristine, and prednisone regimen and was successfully rescured after timely identification and treatment. We emphasize that physicians should be alert for the coinfection of PJP and CMV in lymphoma patients receiving rituximab-based chemotherapy and the timely recognition, and treatment that may avoid a deadly outcome. |
| format | Article |
| id | doaj-art-78c3905f7b1d4819adef5e03cb825db2 |
| institution | Kabale University |
| issn | 2311-3006 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Cancer Research and Practice |
| spelling | doaj-art-78c3905f7b1d4819adef5e03cb825db22025-01-23T05:10:46ZengWolters Kluwer Medknow PublicationsJournal of Cancer Research and Practice2311-30062024-01-01111394310.4103/ejcrp.eJCRP-D-23-00015Life-threatening Pneumocystis jiroveci Pneumonia with Cytomegalovirus Coinfection in a Follicular Lymphoma Patient During Rituximab-based ChemotherapyMu-Chun YangSheng-Kang ChiuJong-Kai HsiaoWoei-Yau KaoIn the era of target therapy, we face the challenge of the risk of opportunistic infection in patients with B-cell lymphoma who receiving rituximab-based chemotherapy. Opportunistic infections such as Pneumocystis jiroveci pneumonia (PJP) and Cytomegalovirus (CMV) pneumonia are life-threatening diseases. However, PJP with CMV coinfection is rare. Here, we report a follicular lymphoma patient who suffered from PJP with CMV coinfection after receiving three cycles of rituximab, cyclophosphamide, vincristine, and prednisone regimen and was successfully rescured after timely identification and treatment. We emphasize that physicians should be alert for the coinfection of PJP and CMV in lymphoma patients receiving rituximab-based chemotherapy and the timely recognition, and treatment that may avoid a deadly outcome.https://journals.lww.com/10.4103/ejcrp.eJCRP-D-23-00015coinfectioncytomegalovirusfollicular lymphomapneumocystis jiroveci pneumoniarituximabcyclophosphamidevincristineand prednisone |
| spellingShingle | Mu-Chun Yang Sheng-Kang Chiu Jong-Kai Hsiao Woei-Yau Kao Life-threatening Pneumocystis jiroveci Pneumonia with Cytomegalovirus Coinfection in a Follicular Lymphoma Patient During Rituximab-based Chemotherapy Journal of Cancer Research and Practice coinfection cytomegalovirus follicular lymphoma pneumocystis jiroveci pneumonia rituximab cyclophosphamide vincristine and prednisone |
| title | Life-threatening Pneumocystis jiroveci Pneumonia with Cytomegalovirus Coinfection in a Follicular Lymphoma Patient During Rituximab-based Chemotherapy |
| title_full | Life-threatening Pneumocystis jiroveci Pneumonia with Cytomegalovirus Coinfection in a Follicular Lymphoma Patient During Rituximab-based Chemotherapy |
| title_fullStr | Life-threatening Pneumocystis jiroveci Pneumonia with Cytomegalovirus Coinfection in a Follicular Lymphoma Patient During Rituximab-based Chemotherapy |
| title_full_unstemmed | Life-threatening Pneumocystis jiroveci Pneumonia with Cytomegalovirus Coinfection in a Follicular Lymphoma Patient During Rituximab-based Chemotherapy |
| title_short | Life-threatening Pneumocystis jiroveci Pneumonia with Cytomegalovirus Coinfection in a Follicular Lymphoma Patient During Rituximab-based Chemotherapy |
| title_sort | life threatening pneumocystis jiroveci pneumonia with cytomegalovirus coinfection in a follicular lymphoma patient during rituximab based chemotherapy |
| topic | coinfection cytomegalovirus follicular lymphoma pneumocystis jiroveci pneumonia rituximab cyclophosphamide vincristine and prednisone |
| url | https://journals.lww.com/10.4103/ejcrp.eJCRP-D-23-00015 |
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