Novel serum biomarkers for early diagnosis of gestational diabetes mellitus—a review
Gestational diabetes mellitus (GDM) affects 9–25% of pregnancies. Undiagnosed or poorly managed GDM is associated with both short- and long-term complications in the fetus and mother. The pathogenesis of GDM is complex and has not yet been fully elucidated. Several biomarkers found in maternal serum...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Gynecological Endocrinology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/09513590.2025.2455472 |
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| author | Michał Kunicki Natalia Rzewuska Paulina Sopońska Agata Pawłosek Iwona Sowińska Anna Kloska |
| author_facet | Michał Kunicki Natalia Rzewuska Paulina Sopońska Agata Pawłosek Iwona Sowińska Anna Kloska |
| author_sort | Michał Kunicki |
| collection | DOAJ |
| description | Gestational diabetes mellitus (GDM) affects 9–25% of pregnancies. Undiagnosed or poorly managed GDM is associated with both short- and long-term complications in the fetus and mother. The pathogenesis of GDM is complex and has not yet been fully elucidated. Several biomarkers found in maternal serum have the potential for the early diagnosis of GDM. The aim of this narrative review was to explore novel biomarkers that have not been comprehensively described in previous reviews. We believe these biomarkers may allow for the detection of GDM in the early stages of pregnancy, enabling timely proper treatment and potentially preventing complications for both the mother and the fetus. |
| format | Article |
| id | doaj-art-78afe9a6d6e84d1b8c66de2ef2962dc8 |
| institution | Kabale University |
| issn | 0951-3590 1473-0766 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Gynecological Endocrinology |
| spelling | doaj-art-78afe9a6d6e84d1b8c66de2ef2962dc82025-01-21T09:01:44ZengTaylor & Francis GroupGynecological Endocrinology0951-35901473-07662025-12-0141110.1080/09513590.2025.2455472Novel serum biomarkers for early diagnosis of gestational diabetes mellitus—a reviewMichał Kunicki0Natalia Rzewuska1Paulina Sopońska2Agata Pawłosek3Iwona Sowińska4Anna Kloska5Department of Gynecological Endocrinology, Medical University of Warsaw, Warsaw, PolandDepartment of Gynecological Endocrinology, Medical University of Warsaw, Warsaw, PolandINVICTA Fertility and Reproductive Center, Gdańsk, PolandINVICTA Fertility and Reproductive Center, Wrocław, PolandINVICTA Fertility and Reproductive Center, Gdańsk, PolandINVICTA Research and Development Center, Sopot, PolandGestational diabetes mellitus (GDM) affects 9–25% of pregnancies. Undiagnosed or poorly managed GDM is associated with both short- and long-term complications in the fetus and mother. The pathogenesis of GDM is complex and has not yet been fully elucidated. Several biomarkers found in maternal serum have the potential for the early diagnosis of GDM. The aim of this narrative review was to explore novel biomarkers that have not been comprehensively described in previous reviews. We believe these biomarkers may allow for the detection of GDM in the early stages of pregnancy, enabling timely proper treatment and potentially preventing complications for both the mother and the fetus.https://www.tandfonline.com/doi/10.1080/09513590.2025.2455472Gestational diabetes mellitusGDMbiomarkersmaternal serumpregnancy complications |
| spellingShingle | Michał Kunicki Natalia Rzewuska Paulina Sopońska Agata Pawłosek Iwona Sowińska Anna Kloska Novel serum biomarkers for early diagnosis of gestational diabetes mellitus—a review Gynecological Endocrinology Gestational diabetes mellitus GDM biomarkers maternal serum pregnancy complications |
| title | Novel serum biomarkers for early diagnosis of gestational diabetes mellitus—a review |
| title_full | Novel serum biomarkers for early diagnosis of gestational diabetes mellitus—a review |
| title_fullStr | Novel serum biomarkers for early diagnosis of gestational diabetes mellitus—a review |
| title_full_unstemmed | Novel serum biomarkers for early diagnosis of gestational diabetes mellitus—a review |
| title_short | Novel serum biomarkers for early diagnosis of gestational diabetes mellitus—a review |
| title_sort | novel serum biomarkers for early diagnosis of gestational diabetes mellitus a review |
| topic | Gestational diabetes mellitus GDM biomarkers maternal serum pregnancy complications |
| url | https://www.tandfonline.com/doi/10.1080/09513590.2025.2455472 |
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