Pregnancy Following Metabolic–Bariatric Surgery in a Woman With Potential Premature Ovarian Failure: A Case Report

Premature ovarian insufficiency (POI) is associated with decreased ovulation in the precursor stage which leads to ovarian failure in the end stage. Metabolic–bariatric surgery (MBS) can improve women’s reproductive status, including the release of sex hormones, ovulation, and fertilization. Here, w...

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Main Authors: Raheleh Moradi, Maryam Kashanian, Somayeh Mokhber, Abdolreza Pazouki
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2024/4707627
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author Raheleh Moradi
Maryam Kashanian
Somayeh Mokhber
Abdolreza Pazouki
author_facet Raheleh Moradi
Maryam Kashanian
Somayeh Mokhber
Abdolreza Pazouki
author_sort Raheleh Moradi
collection DOAJ
description Premature ovarian insufficiency (POI) is associated with decreased ovulation in the precursor stage which leads to ovarian failure in the end stage. Metabolic–bariatric surgery (MBS) can improve women’s reproductive status, including the release of sex hormones, ovulation, and fertilization. Here, we report a spontaneous pregnancy following MBS despite potential ovarian insufficiency. A 38-year-old woman with severe obesity underwent three cycles of assisted reproduction that were not successful. Oligomenorrhea ≥ 4 months, laboratory indices, and previous poor ovarian response approved the diagnosis of diminished ovarian reserve and could be considered as the precursor stage of POI. Then a gastric bypass was applied, and a spontaneous pregnancy occurred in the 22nd month after surgery, with 45.80% reduction in body mass index. MBS in women with obesity and idiopathic ovarian insufficiency may increase the chance of spontaneous ovulation and successful pregnancy.
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spelling doaj-art-7894ee68b7c24828b196f55812486d492025-02-03T12:01:21ZengWileyCase Reports in Surgery2090-69192024-01-01202410.1155/2024/4707627Pregnancy Following Metabolic–Bariatric Surgery in a Woman With Potential Premature Ovarian Failure: A Case ReportRaheleh Moradi0Maryam Kashanian1Somayeh Mokhber2Abdolreza Pazouki3Minimally Invasive Surgery Research CenterShahid Akbarabadi Clinical Research Development Unit (ShCRDU)Minimally Invasive Surgery Research CenterMinimally Invasive Surgery Research CenterPremature ovarian insufficiency (POI) is associated with decreased ovulation in the precursor stage which leads to ovarian failure in the end stage. Metabolic–bariatric surgery (MBS) can improve women’s reproductive status, including the release of sex hormones, ovulation, and fertilization. Here, we report a spontaneous pregnancy following MBS despite potential ovarian insufficiency. A 38-year-old woman with severe obesity underwent three cycles of assisted reproduction that were not successful. Oligomenorrhea ≥ 4 months, laboratory indices, and previous poor ovarian response approved the diagnosis of diminished ovarian reserve and could be considered as the precursor stage of POI. Then a gastric bypass was applied, and a spontaneous pregnancy occurred in the 22nd month after surgery, with 45.80% reduction in body mass index. MBS in women with obesity and idiopathic ovarian insufficiency may increase the chance of spontaneous ovulation and successful pregnancy.http://dx.doi.org/10.1155/2024/4707627
spellingShingle Raheleh Moradi
Maryam Kashanian
Somayeh Mokhber
Abdolreza Pazouki
Pregnancy Following Metabolic–Bariatric Surgery in a Woman With Potential Premature Ovarian Failure: A Case Report
Case Reports in Surgery
title Pregnancy Following Metabolic–Bariatric Surgery in a Woman With Potential Premature Ovarian Failure: A Case Report
title_full Pregnancy Following Metabolic–Bariatric Surgery in a Woman With Potential Premature Ovarian Failure: A Case Report
title_fullStr Pregnancy Following Metabolic–Bariatric Surgery in a Woman With Potential Premature Ovarian Failure: A Case Report
title_full_unstemmed Pregnancy Following Metabolic–Bariatric Surgery in a Woman With Potential Premature Ovarian Failure: A Case Report
title_short Pregnancy Following Metabolic–Bariatric Surgery in a Woman With Potential Premature Ovarian Failure: A Case Report
title_sort pregnancy following metabolic bariatric surgery in a woman with potential premature ovarian failure a case report
url http://dx.doi.org/10.1155/2024/4707627
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AT somayehmokhber pregnancyfollowingmetabolicbariatricsurgeryinawomanwithpotentialprematureovarianfailureacasereport
AT abdolrezapazouki pregnancyfollowingmetabolicbariatricsurgeryinawomanwithpotentialprematureovarianfailureacasereport