Clinical and histopathological manifestations of oral erythroplasia in tobacco smokers
<p><strong>Foundation</strong>: erythroplasia is the most aggressive precancerous lesion in the oral cavity, with great potential for malignant transformation. At the time of performing the biopsy and analyzing the sample, severe dysplasia or invasive carcinoma may appear.<br /&...
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Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2023-07-01
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| Series: | Medisur |
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| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/5755 |
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| author | Gladys Aída Estrada Pereira Liliet Antonia Agüero Despaigne |
| author_facet | Gladys Aída Estrada Pereira Liliet Antonia Agüero Despaigne |
| author_sort | Gladys Aída Estrada Pereira |
| collection | DOAJ |
| description | <p><strong>Foundation</strong>: erythroplasia is the most aggressive precancerous lesion in the oral cavity, with great potential for malignant transformation. At the time of performing the biopsy and analyzing the sample, severe dysplasia or invasive carcinoma may appear.<br /><strong>Objective</strong>: to describe the clinical and histopathological manifestations of oral erythroplasia in patients who are active tobacco smokers.<br /><strong>Methods</strong>: a descriptive and cross-sectional study was carried out, with 12 smokers clinically and histopathologically diagnosed with oral erythroplasia, attended in the Specialties Polyclinic stomatological consultation of the Saturnino Lora Torres Hospital, in Santiago de Cuba. For the collection of the primary data, a survey was made with the variables: age, sex, clinical diagnosis, time in the smoking habit, different ways of consuming tobacco, anatomical location and histopathological study of the disease.<br /><strong>Results</strong>: the male sex, the age group of 60 years old and over, and conventional smokers of 21 and over prevailed. Intense chronic inflammatory infiltrate and severe epithelial dysplasia were the most common tissue changes. The tissue dysplastic signs most involved were alteration of the interpapillary nails, loss of polarity of the basal cells, and hyperplasia of the basal layer cells; while the most relevant cytological dysplastics were hyperchromasia of nuclei and nucleoli, nuclear pleomorphism and increased nucleus-cytoplasm ratio, with the soft palate being the most frequent site.<br /><strong>Conclusions</strong>: all the smoking patients showed erythroplastic lesions on oral clinical examination, which was confirmed by histopathological study.</p> |
| format | Article |
| id | doaj-art-787b85b59aab42e2bcfc5e463c1493e4 |
| institution | Kabale University |
| issn | 1727-897X |
| language | Spanish |
| publishDate | 2023-07-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj-art-787b85b59aab42e2bcfc5e463c1493e42025-01-30T21:29:01ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2023-07-012148428502369Clinical and histopathological manifestations of oral erythroplasia in tobacco smokersGladys Aída Estrada Pereira0Liliet Antonia Agüero Despaigne1Hospital Provincial Clinicoquirúrgico Docente Saturnino Lora Torres. Santiago de CubaHospital Provincial Clinicoquirúrgico Docente Saturnino Lora Torres. Santiago de Cuba<p><strong>Foundation</strong>: erythroplasia is the most aggressive precancerous lesion in the oral cavity, with great potential for malignant transformation. At the time of performing the biopsy and analyzing the sample, severe dysplasia or invasive carcinoma may appear.<br /><strong>Objective</strong>: to describe the clinical and histopathological manifestations of oral erythroplasia in patients who are active tobacco smokers.<br /><strong>Methods</strong>: a descriptive and cross-sectional study was carried out, with 12 smokers clinically and histopathologically diagnosed with oral erythroplasia, attended in the Specialties Polyclinic stomatological consultation of the Saturnino Lora Torres Hospital, in Santiago de Cuba. For the collection of the primary data, a survey was made with the variables: age, sex, clinical diagnosis, time in the smoking habit, different ways of consuming tobacco, anatomical location and histopathological study of the disease.<br /><strong>Results</strong>: the male sex, the age group of 60 years old and over, and conventional smokers of 21 and over prevailed. Intense chronic inflammatory infiltrate and severe epithelial dysplasia were the most common tissue changes. The tissue dysplastic signs most involved were alteration of the interpapillary nails, loss of polarity of the basal cells, and hyperplasia of the basal layer cells; while the most relevant cytological dysplastics were hyperchromasia of nuclei and nucleoli, nuclear pleomorphism and increased nucleus-cytoplasm ratio, with the soft palate being the most frequent site.<br /><strong>Conclusions</strong>: all the smoking patients showed erythroplastic lesions on oral clinical examination, which was confirmed by histopathological study.</p>http://medisur.sld.cu/index.php/medisur/article/view/5755eritroplasiafumar tabacolesiones precancerosasmucosa bucal |
| spellingShingle | Gladys Aída Estrada Pereira Liliet Antonia Agüero Despaigne Clinical and histopathological manifestations of oral erythroplasia in tobacco smokers Medisur eritroplasia fumar tabaco lesiones precancerosas mucosa bucal |
| title | Clinical and histopathological manifestations of oral erythroplasia in tobacco smokers |
| title_full | Clinical and histopathological manifestations of oral erythroplasia in tobacco smokers |
| title_fullStr | Clinical and histopathological manifestations of oral erythroplasia in tobacco smokers |
| title_full_unstemmed | Clinical and histopathological manifestations of oral erythroplasia in tobacco smokers |
| title_short | Clinical and histopathological manifestations of oral erythroplasia in tobacco smokers |
| title_sort | clinical and histopathological manifestations of oral erythroplasia in tobacco smokers |
| topic | eritroplasia fumar tabaco lesiones precancerosas mucosa bucal |
| url | http://medisur.sld.cu/index.php/medisur/article/view/5755 |
| work_keys_str_mv | AT gladysaidaestradapereira clinicalandhistopathologicalmanifestationsoforalerythroplasiaintobaccosmokers AT lilietantoniaaguerodespaigne clinicalandhistopathologicalmanifestationsoforalerythroplasiaintobaccosmokers |