Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in Mice
In the auditory pathway, the commissure of the inferior colliculus (IC) interconnects the two ICs on both sides of the dorsal midbrain. This interconnection could mediate an interaction between the two ICs during sound signal processing. The intercollicular effects evoked by focal electric stimulati...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2016/4195391 |
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| author | Hui-Xian Mei Jia Tang Zi-Ying Fu Liang Cheng Qi-Cai Chen |
| author_facet | Hui-Xian Mei Jia Tang Zi-Ying Fu Liang Cheng Qi-Cai Chen |
| author_sort | Hui-Xian Mei |
| collection | DOAJ |
| description | In the auditory pathway, the commissure of the inferior colliculus (IC) interconnects the two ICs on both sides of the dorsal midbrain. This interconnection could mediate an interaction between the two ICs during sound signal processing. The intercollicular effects evoked by focal electric stimulation for 30 min could inhibit or facilitate auditory responses and induce plastic changes in the response minimum threshold (MT) of IC neurons. Changes in MT are dependent on the best frequency (BF) and MT difference. The MT shift is larger in IC neurons with BF differences ≤2 kHz than in those with BF differences >2 kHz. Moreover, MTs that shift toward electrically stimulated IC neurons increase with the increasing MT difference between the two ICs. The shift in MT lasts for a certain period of time and then returns to previous levels within ~150 min. The collicular interactions are either reciprocal or unilateral under alternate stimulating and recording conditions in both ICs. Our results suggest that intercollicular effects may be involved in the acoustic experience-dependent plasticity of the MT of IC neurons. |
| format | Article |
| id | doaj-art-787a807f8bee413db26059c51cc45e7a |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-787a807f8bee413db26059c51cc45e7a2025-02-03T01:02:43ZengWileyNeural Plasticity2090-59041687-54432016-01-01201610.1155/2016/41953914195391Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in MiceHui-Xian Mei0Jia Tang1Zi-Ying Fu2Liang Cheng3Qi-Cai Chen4School of Life Sciences and Hubei Key Lab of Genetic Regulation and Integrative Biology, Central China Normal University, Wuhan 430079, ChinaSchool of Life Sciences and Hubei Key Lab of Genetic Regulation and Integrative Biology, Central China Normal University, Wuhan 430079, ChinaSchool of Life Sciences and Hubei Key Lab of Genetic Regulation and Integrative Biology, Central China Normal University, Wuhan 430079, ChinaSchool of Life Sciences and Hubei Key Lab of Genetic Regulation and Integrative Biology, Central China Normal University, Wuhan 430079, ChinaSchool of Life Sciences and Hubei Key Lab of Genetic Regulation and Integrative Biology, Central China Normal University, Wuhan 430079, ChinaIn the auditory pathway, the commissure of the inferior colliculus (IC) interconnects the two ICs on both sides of the dorsal midbrain. This interconnection could mediate an interaction between the two ICs during sound signal processing. The intercollicular effects evoked by focal electric stimulation for 30 min could inhibit or facilitate auditory responses and induce plastic changes in the response minimum threshold (MT) of IC neurons. Changes in MT are dependent on the best frequency (BF) and MT difference. The MT shift is larger in IC neurons with BF differences ≤2 kHz than in those with BF differences >2 kHz. Moreover, MTs that shift toward electrically stimulated IC neurons increase with the increasing MT difference between the two ICs. The shift in MT lasts for a certain period of time and then returns to previous levels within ~150 min. The collicular interactions are either reciprocal or unilateral under alternate stimulating and recording conditions in both ICs. Our results suggest that intercollicular effects may be involved in the acoustic experience-dependent plasticity of the MT of IC neurons.http://dx.doi.org/10.1155/2016/4195391 |
| spellingShingle | Hui-Xian Mei Jia Tang Zi-Ying Fu Liang Cheng Qi-Cai Chen Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in Mice Neural Plasticity |
| title | Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in Mice |
| title_full | Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in Mice |
| title_fullStr | Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in Mice |
| title_full_unstemmed | Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in Mice |
| title_short | Plastic Change in the Auditory Minimum Threshold Induced by Intercollicular Effects in Mice |
| title_sort | plastic change in the auditory minimum threshold induced by intercollicular effects in mice |
| url | http://dx.doi.org/10.1155/2016/4195391 |
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