Male Child with Van Wyk-Grumbach's Syndrome and Other Complications of Long-Standing Primary Hypothyroidism: A Case Report
Primary hypothyroidism in the juvenile population generally leads to retardation of linear growth and delay or even arrest of puberty. However, in rare conditions, children with long-standing hypothyroidism present with signs of Van Wyk-Grumbach's syndrome (VWGS) which include juvenile hypothyr...
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Format: | Article |
Language: | English |
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Wiley
2012-01-01
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Series: | Case Reports in Pediatrics |
Online Access: | http://dx.doi.org/10.1155/2012/352751 |
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author | Ahmed Omran Jing Peng Biswas Shrestha Muhammad Usman Ashhab Fei Yin |
author_facet | Ahmed Omran Jing Peng Biswas Shrestha Muhammad Usman Ashhab Fei Yin |
author_sort | Ahmed Omran |
collection | DOAJ |
description | Primary hypothyroidism in the juvenile population generally leads to retardation of linear growth and delay or even arrest of puberty. However, in rare conditions, children with long-standing hypothyroidism present with signs of Van Wyk-Grumbach's syndrome (VWGS) which include juvenile hypothyroidism, delayed bone age, and pseudoprecocious puberty. We report a rare case of prepubertal male child from Asian origin, presented with long-standing untreated hypothyroidism complicated with VWGS and other complications including obesity, short stature, hepatomegaly, asymptomatic mild pericardial effusion, and pituitary hyperplasia. |
format | Article |
id | doaj-art-7855658d511f4138be3dbd865006b69e |
institution | Kabale University |
issn | 2090-6803 2090-6811 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Pediatrics |
spelling | doaj-art-7855658d511f4138be3dbd865006b69e2025-02-03T06:06:47ZengWileyCase Reports in Pediatrics2090-68032090-68112012-01-01201210.1155/2012/352751352751Male Child with Van Wyk-Grumbach's Syndrome and Other Complications of Long-Standing Primary Hypothyroidism: A Case ReportAhmed Omran0Jing Peng1Biswas Shrestha2Muhammad Usman Ashhab3Fei Yin4Department of Pediatrics, Xiangya Hospital of Central South University, No. 87 Xiangya Road, Changsha, Hunan 410008, ChinaDepartment of Pediatrics, Xiangya Hospital of Central South University, No. 87 Xiangya Road, Changsha, Hunan 410008, ChinaDepartment of Radiology, Third Xiangya Hospital of Central South University, Changsha, Hunan 410008, ChinaDepartment of Pediatrics, Xiangya Hospital of Central South University, No. 87 Xiangya Road, Changsha, Hunan 410008, ChinaDepartment of Pediatrics, Xiangya Hospital of Central South University, No. 87 Xiangya Road, Changsha, Hunan 410008, ChinaPrimary hypothyroidism in the juvenile population generally leads to retardation of linear growth and delay or even arrest of puberty. However, in rare conditions, children with long-standing hypothyroidism present with signs of Van Wyk-Grumbach's syndrome (VWGS) which include juvenile hypothyroidism, delayed bone age, and pseudoprecocious puberty. We report a rare case of prepubertal male child from Asian origin, presented with long-standing untreated hypothyroidism complicated with VWGS and other complications including obesity, short stature, hepatomegaly, asymptomatic mild pericardial effusion, and pituitary hyperplasia.http://dx.doi.org/10.1155/2012/352751 |
spellingShingle | Ahmed Omran Jing Peng Biswas Shrestha Muhammad Usman Ashhab Fei Yin Male Child with Van Wyk-Grumbach's Syndrome and Other Complications of Long-Standing Primary Hypothyroidism: A Case Report Case Reports in Pediatrics |
title | Male Child with Van Wyk-Grumbach's Syndrome and Other Complications of Long-Standing Primary Hypothyroidism: A Case Report |
title_full | Male Child with Van Wyk-Grumbach's Syndrome and Other Complications of Long-Standing Primary Hypothyroidism: A Case Report |
title_fullStr | Male Child with Van Wyk-Grumbach's Syndrome and Other Complications of Long-Standing Primary Hypothyroidism: A Case Report |
title_full_unstemmed | Male Child with Van Wyk-Grumbach's Syndrome and Other Complications of Long-Standing Primary Hypothyroidism: A Case Report |
title_short | Male Child with Van Wyk-Grumbach's Syndrome and Other Complications of Long-Standing Primary Hypothyroidism: A Case Report |
title_sort | male child with van wyk grumbach s syndrome and other complications of long standing primary hypothyroidism a case report |
url | http://dx.doi.org/10.1155/2012/352751 |
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