A Case of Distal Epithelioid Sarcoma of the Thumb Expressing Podoplanin, TLE1 and Ca 125
Distal epithelioid sarcoma is a rare and slowly growing tumor that usually develops in the upper extremities of young adults. Neoplastic cells have both spindle and epithelioid appearance and are characterized by the loss of the nuclear protein SMARCB1/INI1. We present the case of a distal epithelio...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2013/312786 |
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| author | George Karagkounis Theodore Argyrakos G. Charkiolakis O. Castana D. Rontogianni |
| author_facet | George Karagkounis Theodore Argyrakos G. Charkiolakis O. Castana D. Rontogianni |
| author_sort | George Karagkounis |
| collection | DOAJ |
| description | Distal epithelioid sarcoma is a rare and slowly growing tumor that usually develops in the upper extremities of young adults. Neoplastic cells have both spindle and epithelioid appearance and are characterized by the loss of the nuclear protein SMARCB1/INI1. We present the case of a distal epithelioid sarcoma arising in the thumb of a 14-year-old girl, which immunohistochemically was characterized by the loss of SMARCB1/INI1 protein as well as the expression of podoplanin (D2-40), TLE1, Glut1, and Ca 125; plus, we highlight the differential diagnosis of epithelioid sarcoma from its histological mimics. |
| format | Article |
| id | doaj-art-782ca077b85b43458eb969c909012b3b |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-782ca077b85b43458eb969c909012b3b2025-02-03T05:58:18ZengWileyCase Reports in Pathology2090-67812090-679X2013-01-01201310.1155/2013/312786312786A Case of Distal Epithelioid Sarcoma of the Thumb Expressing Podoplanin, TLE1 and Ca 125George Karagkounis0Theodore Argyrakos1G. Charkiolakis2O. Castana3D. Rontogianni4Department of Pathology, Evaggelismos Hospital, Ipsilantoy 45-47, 106 76 Athens, GreeceDepartment of Pathology, Evaggelismos Hospital, Ipsilantoy 45-47, 106 76 Athens, GreeceDepartment of Plastic Surgery, Evaggelismos Hospital, Ipsilantoy 45-47, 106 76 Athens, GreeceDepartment of Plastic Surgery, Evaggelismos Hospital, Ipsilantoy 45-47, 106 76 Athens, GreeceDepartment of Pathology, Evaggelismos Hospital, Ipsilantoy 45-47, 106 76 Athens, GreeceDistal epithelioid sarcoma is a rare and slowly growing tumor that usually develops in the upper extremities of young adults. Neoplastic cells have both spindle and epithelioid appearance and are characterized by the loss of the nuclear protein SMARCB1/INI1. We present the case of a distal epithelioid sarcoma arising in the thumb of a 14-year-old girl, which immunohistochemically was characterized by the loss of SMARCB1/INI1 protein as well as the expression of podoplanin (D2-40), TLE1, Glut1, and Ca 125; plus, we highlight the differential diagnosis of epithelioid sarcoma from its histological mimics.http://dx.doi.org/10.1155/2013/312786 |
| spellingShingle | George Karagkounis Theodore Argyrakos G. Charkiolakis O. Castana D. Rontogianni A Case of Distal Epithelioid Sarcoma of the Thumb Expressing Podoplanin, TLE1 and Ca 125 Case Reports in Pathology |
| title | A Case of Distal Epithelioid Sarcoma of the Thumb Expressing Podoplanin, TLE1 and Ca 125 |
| title_full | A Case of Distal Epithelioid Sarcoma of the Thumb Expressing Podoplanin, TLE1 and Ca 125 |
| title_fullStr | A Case of Distal Epithelioid Sarcoma of the Thumb Expressing Podoplanin, TLE1 and Ca 125 |
| title_full_unstemmed | A Case of Distal Epithelioid Sarcoma of the Thumb Expressing Podoplanin, TLE1 and Ca 125 |
| title_short | A Case of Distal Epithelioid Sarcoma of the Thumb Expressing Podoplanin, TLE1 and Ca 125 |
| title_sort | case of distal epithelioid sarcoma of the thumb expressing podoplanin tle1 and ca 125 |
| url | http://dx.doi.org/10.1155/2013/312786 |
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