The Natural History and Treatment Options for Unruptured Intracranial Aneurysms

Recent advances in angiographic technique have raised our awareness of the presence of unruptured intracranial aneurysms (UIAs). However, the appropriate management for these lesions remains controversial. To optimize patient outcomes, the physician must weigh aneurysmal rupture risk associated with...

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Main Authors: Joshua E. Loewenstein, Shaneze C. Gayle, E. Jesus Duffis, Charles J. Prestigiacomo, Chirag D. Gandhi
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Vascular Medicine
Online Access:http://dx.doi.org/10.1155/2012/898052
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author Joshua E. Loewenstein
Shaneze C. Gayle
E. Jesus Duffis
Charles J. Prestigiacomo
Chirag D. Gandhi
author_facet Joshua E. Loewenstein
Shaneze C. Gayle
E. Jesus Duffis
Charles J. Prestigiacomo
Chirag D. Gandhi
author_sort Joshua E. Loewenstein
collection DOAJ
description Recent advances in angiographic technique have raised our awareness of the presence of unruptured intracranial aneurysms (UIAs). However, the appropriate management for these lesions remains controversial. To optimize patient outcomes, the physician must weigh aneurysmal rupture risk associated with observation against the complication risks associated with intervention. In the case that treatment is chosen, the two available options are surgical clipping and endovascular coiling. Our paper summarizes the current body of literature in regards to the natural history of UIAs, the evolution of the lesion if it progresses uninterrupted, as well as the safety and efficacy of both treatment options. The risks and benefits of treatment and conservative management need to be evaluated on an individual basis and are greatly effected by both patient-specific and aneurysm-specific factors, which are presented in this paper. Ultimately, this body of data has led to multiple sets of treatment guidelines, which we have summated and presented in this paper.
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publishDate 2012-01-01
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spelling doaj-art-78179cddd8cf4bffb40373d65215f59c2025-02-03T00:59:02ZengWileyInternational Journal of Vascular Medicine2090-28242090-28322012-01-01201210.1155/2012/898052898052The Natural History and Treatment Options for Unruptured Intracranial AneurysmsJoshua E. Loewenstein0Shaneze C. Gayle1E. Jesus Duffis2Charles J. Prestigiacomo3Chirag D. Gandhi4Department of Neurological Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07101, USADepartment of Neurological Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07101, USADepartment of Neurological Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07101, USADepartment of Neurological Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07101, USADepartment of Neurological Surgery, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07101, USARecent advances in angiographic technique have raised our awareness of the presence of unruptured intracranial aneurysms (UIAs). However, the appropriate management for these lesions remains controversial. To optimize patient outcomes, the physician must weigh aneurysmal rupture risk associated with observation against the complication risks associated with intervention. In the case that treatment is chosen, the two available options are surgical clipping and endovascular coiling. Our paper summarizes the current body of literature in regards to the natural history of UIAs, the evolution of the lesion if it progresses uninterrupted, as well as the safety and efficacy of both treatment options. The risks and benefits of treatment and conservative management need to be evaluated on an individual basis and are greatly effected by both patient-specific and aneurysm-specific factors, which are presented in this paper. Ultimately, this body of data has led to multiple sets of treatment guidelines, which we have summated and presented in this paper.http://dx.doi.org/10.1155/2012/898052
spellingShingle Joshua E. Loewenstein
Shaneze C. Gayle
E. Jesus Duffis
Charles J. Prestigiacomo
Chirag D. Gandhi
The Natural History and Treatment Options for Unruptured Intracranial Aneurysms
International Journal of Vascular Medicine
title The Natural History and Treatment Options for Unruptured Intracranial Aneurysms
title_full The Natural History and Treatment Options for Unruptured Intracranial Aneurysms
title_fullStr The Natural History and Treatment Options for Unruptured Intracranial Aneurysms
title_full_unstemmed The Natural History and Treatment Options for Unruptured Intracranial Aneurysms
title_short The Natural History and Treatment Options for Unruptured Intracranial Aneurysms
title_sort natural history and treatment options for unruptured intracranial aneurysms
url http://dx.doi.org/10.1155/2012/898052
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