Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study
Abstract Aims The aim of this pilot study was to investigate the safety, feasibility, tolerability, and acceptability of an assisted mobilization of advanced heart failure patients, using a lightweight, exoskeleton‐type robot (Myosuit, MyoSwiss AG, Zurich, Switzerland). Methods and results Twenty pa...
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| Format: | Article |
| Language: | English |
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Wiley
2022-06-01
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| Series: | ESC Heart Failure |
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| Online Access: | https://doi.org/10.1002/ehf2.13903 |
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| author | Isabell Anna Just Denis Fries Sina Loewe Volkmar Falk Nikola Cesarovic Frank Edelmann Anna Feuerstein Florian L. Haufe Michele Xiloyannis Robert Riener Felix Schoenrath |
| author_facet | Isabell Anna Just Denis Fries Sina Loewe Volkmar Falk Nikola Cesarovic Frank Edelmann Anna Feuerstein Florian L. Haufe Michele Xiloyannis Robert Riener Felix Schoenrath |
| author_sort | Isabell Anna Just |
| collection | DOAJ |
| description | Abstract Aims The aim of this pilot study was to investigate the safety, feasibility, tolerability, and acceptability of an assisted mobilization of advanced heart failure patients, using a lightweight, exoskeleton‐type robot (Myosuit, MyoSwiss AG, Zurich, Switzerland). Methods and results Twenty patients in functional NYHA class III performed activities of daily life (ADL, n = 10) or participated in a single, standardized, 60 min rehabilitation exercise unit (REU, n = 10) with and without the Myosuit. The outcome assessment included the evaluation of vital signs, adverse events, rates of perceived exertion and dyspnoea (RPE, RPD), the ability to perform ADL or REU, and the individual acceptability. The mean age of the subjects was 49.4 (±11.0) years; 80% were male. The mean left ventricular ejection fraction was 22.1% (±7.4%) and the median NT‐proBNP 2054 pg/mL (IQR 677, 3270 pg/mL). In all patients, mobilization with the Myosuit was feasible independently or with minor support. The mean individual difference in the total walking distance of the patients without and with robotic assistance was −26.5 m (95% confidence interval (CI) −142 to 78 m, P = 0.241). No adverse events occurred. RPE and RPD showed no significant difference with or without the device (ADL: RPE −0.1 m, 95% CI −1.42 to 1.62, P = 0.932 and RPD −0.95 m, 95% CI −0.38 to 2.28, P = 0.141; REU: RPE 1.1 m, 95% CI −2.90 to 0.70, P = 0.201 and RPD 0.5 m, 95% CI −2.02 to 1.02, P = 0.435). All median responses in the acceptability questionnaire were positive. The patients felt safe and enjoyed the experience; 85% would be interested in participating in robot‐assisted training on a regular basis. Conclusion This feasibility pilot trial provides first indications that a robotic exoskeleton‐assisted mobilization of patients with advanced heart failure is safe, feasible, well‐tolerated, and well‐accepted. The results are highly encouraging to further pursue this innovative approach in rehabilitation programmes. This trial was registered at ClinicalTrials.gov: NCT04839133. |
| format | Article |
| id | doaj-art-78179bedac4e41d589a2ad73aa224f36 |
| institution | Kabale University |
| issn | 2055-5822 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Wiley |
| record_format | Article |
| series | ESC Heart Failure |
| spelling | doaj-art-78179bedac4e41d589a2ad73aa224f362025-02-05T05:22:10ZengWileyESC Heart Failure2055-58222022-06-01931643165010.1002/ehf2.13903Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot studyIsabell Anna Just0Denis Fries1Sina Loewe2Volkmar Falk3Nikola Cesarovic4Frank Edelmann5Anna Feuerstein6Florian L. Haufe7Michele Xiloyannis8Robert Riener9Felix Schoenrath10Department of Cardiothoracic and Vascular Surgery German Heart Center Berlin Berlin GermanyDepartment of Cardiothoracic and Vascular Surgery German Heart Center Berlin Berlin GermanyDepartment of Cardiothoracic and Vascular Surgery German Heart Center Berlin Berlin GermanyDepartment of Cardiothoracic and Vascular Surgery German Heart Center Berlin Berlin GermanyDepartment of Cardiothoracic and Vascular Surgery German Heart Center Berlin Berlin GermanyDepartment of Cardiology Charité‐Universitätsmedizin Berlin Berlin GermanyDZHK (German Centre for Cardiovascular Research), Partner Site Berlin Berlin GermanySensory‐Motor Systems (SMS) Lab, Institute of Robotics and Intelligent Systems (IRIS) ETH Zürich Zürich SwitzerlandSensory‐Motor Systems (SMS) Lab, Institute of Robotics and Intelligent Systems (IRIS) ETH Zürich Zürich SwitzerlandSensory‐Motor Systems (SMS) Lab, Institute of Robotics and Intelligent Systems (IRIS) ETH Zürich Zürich SwitzerlandDepartment of Cardiothoracic and Vascular Surgery German Heart Center Berlin Berlin GermanyAbstract Aims The aim of this pilot study was to investigate the safety, feasibility, tolerability, and acceptability of an assisted mobilization of advanced heart failure patients, using a lightweight, exoskeleton‐type robot (Myosuit, MyoSwiss AG, Zurich, Switzerland). Methods and results Twenty patients in functional NYHA class III performed activities of daily life (ADL, n = 10) or participated in a single, standardized, 60 min rehabilitation exercise unit (REU, n = 10) with and without the Myosuit. The outcome assessment included the evaluation of vital signs, adverse events, rates of perceived exertion and dyspnoea (RPE, RPD), the ability to perform ADL or REU, and the individual acceptability. The mean age of the subjects was 49.4 (±11.0) years; 80% were male. The mean left ventricular ejection fraction was 22.1% (±7.4%) and the median NT‐proBNP 2054 pg/mL (IQR 677, 3270 pg/mL). In all patients, mobilization with the Myosuit was feasible independently or with minor support. The mean individual difference in the total walking distance of the patients without and with robotic assistance was −26.5 m (95% confidence interval (CI) −142 to 78 m, P = 0.241). No adverse events occurred. RPE and RPD showed no significant difference with or without the device (ADL: RPE −0.1 m, 95% CI −1.42 to 1.62, P = 0.932 and RPD −0.95 m, 95% CI −0.38 to 2.28, P = 0.141; REU: RPE 1.1 m, 95% CI −2.90 to 0.70, P = 0.201 and RPD 0.5 m, 95% CI −2.02 to 1.02, P = 0.435). All median responses in the acceptability questionnaire were positive. The patients felt safe and enjoyed the experience; 85% would be interested in participating in robot‐assisted training on a regular basis. Conclusion This feasibility pilot trial provides first indications that a robotic exoskeleton‐assisted mobilization of patients with advanced heart failure is safe, feasible, well‐tolerated, and well‐accepted. The results are highly encouraging to further pursue this innovative approach in rehabilitation programmes. This trial was registered at ClinicalTrials.gov: NCT04839133.https://doi.org/10.1002/ehf2.13903Heart failureExoskeletonRobotic‐assistedRehabilitationExercise trainingMyosuit |
| spellingShingle | Isabell Anna Just Denis Fries Sina Loewe Volkmar Falk Nikola Cesarovic Frank Edelmann Anna Feuerstein Florian L. Haufe Michele Xiloyannis Robert Riener Felix Schoenrath Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study ESC Heart Failure Heart failure Exoskeleton Robotic‐assisted Rehabilitation Exercise training Myosuit |
| title | Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study |
| title_full | Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study |
| title_fullStr | Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study |
| title_full_unstemmed | Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study |
| title_short | Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study |
| title_sort | movement therapy in advanced heart failure assisted by a lightweight wearable robot a feasibility pilot study |
| topic | Heart failure Exoskeleton Robotic‐assisted Rehabilitation Exercise training Myosuit |
| url | https://doi.org/10.1002/ehf2.13903 |
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