Probiotic Prophylaxis of Neonatal Jaundice

We investigated the effect of the administration of probiotics (PB) for the prevention of neonatal jaundice (NJ) in 315 full-term newborns (NBs). We grouped them according to the type and duration of PB intake: A – 5 days L. rhamnosus; B – 5 days L. reteri; C – 5 days B. animalis; D – 30 days L. rha...

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Main Authors: Tatyana Itova, Victoria Georgieva
Format: Article
Language:English
Published: Medical University - Pleven 2022-11-01
Series:Journal of Biomedical & Clinical Research
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Online Access:https://jbcr.arphahub.com/article/34654/download/pdf/
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author Tatyana Itova
Victoria Georgieva
author_facet Tatyana Itova
Victoria Georgieva
author_sort Tatyana Itova
collection DOAJ
description We investigated the effect of the administration of probiotics (PB) for the prevention of neonatal jaundice (NJ) in 315 full-term newborns (NBs). We grouped them according to the type and duration of PB intake: A – 5 days L. rhamnosus; B – 5 days L. reteri; C – 5 days B. animalis; D – 30 days L. rhamnosus; E – 30 days L. reuteri, F – 30 days B. animalis; G – without PB. Bilirubin (BR) was measured from 1st to 5th, on 14th, and on 28th day. The incidence of pathologic NJ in groups A&D, B&E, C&F, and G was 37, 36, 29, and 44%, respectively. During first five days, the lowest BR levels were found in Group C, the highest in Group G. BR levels on 14th and 28th days were not significantly different between groups A and D, B and E, C and F. The lowest levels of BR on the same days were found in group F and the highest in group E. The prophylactic use of L. rhamnosus, L. reuteri and B. animalis in full-term NBs significantly reduced the incidence and continuance of NJ. Duration of taking PB significantly affects the development of NJ. The most pronounced effect was when B. animalis was added.
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spelling doaj-art-780a774d16b3473faf24d58afeab265e2025-08-20T03:55:48ZengMedical University - PlevenJournal of Biomedical & Clinical Research1313-90532022-11-0115215816410.2478/jbcr-2022-002234654Probiotic Prophylaxis of Neonatal JaundiceTatyana ItovaVictoria GeorgievaWe investigated the effect of the administration of probiotics (PB) for the prevention of neonatal jaundice (NJ) in 315 full-term newborns (NBs). We grouped them according to the type and duration of PB intake: A – 5 days L. rhamnosus; B – 5 days L. reteri; C – 5 days B. animalis; D – 30 days L. rhamnosus; E – 30 days L. reuteri, F – 30 days B. animalis; G – without PB. Bilirubin (BR) was measured from 1st to 5th, on 14th, and on 28th day. The incidence of pathologic NJ in groups A&D, B&E, C&F, and G was 37, 36, 29, and 44%, respectively. During first five days, the lowest BR levels were found in Group C, the highest in Group G. BR levels on 14th and 28th days were not significantly different between groups A and D, B and E, C and F. The lowest levels of BR on the same days were found in group F and the highest in group E. The prophylactic use of L. rhamnosus, L. reuteri and B. animalis in full-term NBs significantly reduced the incidence and continuance of NJ. Duration of taking PB significantly affects the development of NJ. The most pronounced effect was when B. animalis was added.https://jbcr.arphahub.com/article/34654/download/pdf/jaundiceprobioticnewborn
spellingShingle Tatyana Itova
Victoria Georgieva
Probiotic Prophylaxis of Neonatal Jaundice
Journal of Biomedical & Clinical Research
jaundice
probiotic
newborn
title Probiotic Prophylaxis of Neonatal Jaundice
title_full Probiotic Prophylaxis of Neonatal Jaundice
title_fullStr Probiotic Prophylaxis of Neonatal Jaundice
title_full_unstemmed Probiotic Prophylaxis of Neonatal Jaundice
title_short Probiotic Prophylaxis of Neonatal Jaundice
title_sort probiotic prophylaxis of neonatal jaundice
topic jaundice
probiotic
newborn
url https://jbcr.arphahub.com/article/34654/download/pdf/
work_keys_str_mv AT tatyanaitova probioticprophylaxisofneonataljaundice
AT victoriageorgieva probioticprophylaxisofneonataljaundice