Chronic consumption of thermally processed palm oil or canola oil modified gut microflora of rats
Dietary oils have critical influences on human health, and thermally cooking or frying modify the components and nutritional functions of oils. Palm oil was the most widely used oil in food processing industry, but its health effects remain debatable. In the current study, we aimed to compare the ef...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2021-01-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453020301713 |
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| author | Mengcheng Ruan Yiran Bu Fangjie Wu Shijie Zhang Rulong Chen Na Li Zhiguo Liu Hualin Wang |
| author_facet | Mengcheng Ruan Yiran Bu Fangjie Wu Shijie Zhang Rulong Chen Na Li Zhiguo Liu Hualin Wang |
| author_sort | Mengcheng Ruan |
| collection | DOAJ |
| description | Dietary oils have critical influences on human health, and thermally cooking or frying modify the components and nutritional functions of oils. Palm oil was the most widely used oil in food processing industry, but its health effects remain debatable. In the current study, we aimed to compare the effects of thermally oxidized palm oil and canola oil on gut microbiota. Palm oil or canola oil were heated at 180 °C for 10 h to prepare high-fat diets. Rats were fed high-fat diets for 3 months, and hematological properties, gut microflora composition and intestinal gene expression were examined. The results indicated that heated canola oil consumption elevated plasma total cholesterol and LDL-c levels compared with unheated canola oil, but heated palm oil do not had these effects; and consumption of heated palm oil significantly elevated the relative abundance of Lactobacillucs and Roseburia in gut, compared with non-heated palm oil or two canola oil groups. Moreover, intestinal expression of IL-22 was increased in heated palm oil fed animal, though ZO-1 and GPR41 were reduced. In conclusion, heating process may enhance the effects of palm oil on proliferation of probiotics Lactobacillucs, and weaken the effects of canola oil on cholesterol transport and metabolism. |
| format | Article |
| id | doaj-art-77fbd36857fc4b96b1878b33b978914f |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-77fbd36857fc4b96b1878b33b978914f2025-02-03T02:33:31ZengTsinghua University PressFood Science and Human Wellness2213-45302021-01-0110194102Chronic consumption of thermally processed palm oil or canola oil modified gut microflora of ratsMengcheng Ruan0Yiran Bu1Fangjie Wu2Shijie Zhang3Rulong Chen4Na Li5Zhiguo Liu6Hualin Wang7School of Biology and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan, Hubei, 430023, ChinaSchool of Biology and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan, Hubei, 430023, ChinaHubei Provincial Key Laboratory for Applied Toxicology, Hubei Provincial Academy of Preventive Medicine, Wuhan 430079, China; Hubei Research Centre for Laboratory Animal, Wuhan 430079, ChinaSchool of Biology and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan, Hubei, 430023, ChinaSchool of Biology and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan, Hubei, 430023, ChinaSchool of Biology and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan, Hubei, 430023, ChinaSchool of Biology and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan, Hubei, 430023, China; Corresponding authors.School of Biology and Pharmaceutical Engineering, Wuhan Polytechnic University, Wuhan, Hubei, 430023, China; Corresponding authors.Dietary oils have critical influences on human health, and thermally cooking or frying modify the components and nutritional functions of oils. Palm oil was the most widely used oil in food processing industry, but its health effects remain debatable. In the current study, we aimed to compare the effects of thermally oxidized palm oil and canola oil on gut microbiota. Palm oil or canola oil were heated at 180 °C for 10 h to prepare high-fat diets. Rats were fed high-fat diets for 3 months, and hematological properties, gut microflora composition and intestinal gene expression were examined. The results indicated that heated canola oil consumption elevated plasma total cholesterol and LDL-c levels compared with unheated canola oil, but heated palm oil do not had these effects; and consumption of heated palm oil significantly elevated the relative abundance of Lactobacillucs and Roseburia in gut, compared with non-heated palm oil or two canola oil groups. Moreover, intestinal expression of IL-22 was increased in heated palm oil fed animal, though ZO-1 and GPR41 were reduced. In conclusion, heating process may enhance the effects of palm oil on proliferation of probiotics Lactobacillucs, and weaken the effects of canola oil on cholesterol transport and metabolism.http://www.sciencedirect.com/science/article/pii/S2213453020301713Palm oilCanola oilGut microbiotaShort-chain fatty acidsThermally oxidized oils |
| spellingShingle | Mengcheng Ruan Yiran Bu Fangjie Wu Shijie Zhang Rulong Chen Na Li Zhiguo Liu Hualin Wang Chronic consumption of thermally processed palm oil or canola oil modified gut microflora of rats Food Science and Human Wellness Palm oil Canola oil Gut microbiota Short-chain fatty acids Thermally oxidized oils |
| title | Chronic consumption of thermally processed palm oil or canola oil modified gut microflora of rats |
| title_full | Chronic consumption of thermally processed palm oil or canola oil modified gut microflora of rats |
| title_fullStr | Chronic consumption of thermally processed palm oil or canola oil modified gut microflora of rats |
| title_full_unstemmed | Chronic consumption of thermally processed palm oil or canola oil modified gut microflora of rats |
| title_short | Chronic consumption of thermally processed palm oil or canola oil modified gut microflora of rats |
| title_sort | chronic consumption of thermally processed palm oil or canola oil modified gut microflora of rats |
| topic | Palm oil Canola oil Gut microbiota Short-chain fatty acids Thermally oxidized oils |
| url | http://www.sciencedirect.com/science/article/pii/S2213453020301713 |
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