Targeting the UCP1-dependent thermogenesis pathway with CRISPR/Cas9: a new approach to obesity management

Targeting the UCP1-dependent thermogenesis pathway with CRISPR/Cas9: a new approach to obesity management

Obesity is a complex, multifactorial disease characterized by excessive body fat accumulation, which negatively impacts health. Its increasing prevalence has led to a global epidemic, emphasizing the urgent need for innovative and effective treatment strategies. This study aims to explore the potent...

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Bibliographic Details
Main Authors: Esmail Karami, Fatemeh Rostamkhani, Maasoume Abdollahi, Mohamadreza Ahmadifard
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Biotechnology
Subjects:
Obesity
UCP1
Thermogenesis
CRISPR/Cas9
Gene therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2590262825000267
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