A Rare Presentation of Hepatitis A Infection with Extrahepatic Manifestations

Hepatitis A has a variety of associated extrahepatic manifestations that clinicians should be aware of for early diagnosis and treatment. We report a unique case of hepatitis A presenting with multiple extrahepatic manifestations not previously described in a single patient. A 34-year-old male prese...

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Main Authors: Geetika Bhatt, Varrinder S. Sandhu, Charlene K. Mitchell
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2014/286914
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author Geetika Bhatt
Varrinder S. Sandhu
Charlene K. Mitchell
author_facet Geetika Bhatt
Varrinder S. Sandhu
Charlene K. Mitchell
author_sort Geetika Bhatt
collection DOAJ
description Hepatitis A has a variety of associated extrahepatic manifestations that clinicians should be aware of for early diagnosis and treatment. We report a unique case of hepatitis A presenting with multiple extrahepatic manifestations not previously described in a single patient. A 34-year-old male presented with sudden onset of left sided facial pain, swelling, and skin rash, with diffuse body pains and muscle weakness, and was found to be positive for hepatitis A immunoglobulin M (IgM). He was initially started on antibiotics for concerns of bacterial parotitis but did not show any improvement. A punch biopsy of his mandibular rash and swelling was done which showed lymphohistiocytic infiltration with a few eosinophils. A trial of prednisone resulted in improvement of his symptoms. Clinicians should be aware to look for hepatitis A infection in a patient with atypical clinical picture causing a widespread systemic inflammatory response. Treatment with prednisone may result in resolution.
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spelling doaj-art-77eec35eef764e5a98406338f6ba0aa12025-02-03T01:02:08ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362014-01-01201410.1155/2014/286914286914A Rare Presentation of Hepatitis A Infection with Extrahepatic ManifestationsGeetika Bhatt0Varrinder S. Sandhu1Charlene K. Mitchell2Department of Internal Medicine, University of Louisville, 529 South Jackson Street, Louisville, KY 40202, USADepartment of Internal Medicine, University of Louisville, 529 South Jackson Street, Louisville, KY 40202, USAMedicine and Pediatrics, Department of Internal Medicine, University of Louisville, 529 South Jackson Street, Louisville, KY 40202, USAHepatitis A has a variety of associated extrahepatic manifestations that clinicians should be aware of for early diagnosis and treatment. We report a unique case of hepatitis A presenting with multiple extrahepatic manifestations not previously described in a single patient. A 34-year-old male presented with sudden onset of left sided facial pain, swelling, and skin rash, with diffuse body pains and muscle weakness, and was found to be positive for hepatitis A immunoglobulin M (IgM). He was initially started on antibiotics for concerns of bacterial parotitis but did not show any improvement. A punch biopsy of his mandibular rash and swelling was done which showed lymphohistiocytic infiltration with a few eosinophils. A trial of prednisone resulted in improvement of his symptoms. Clinicians should be aware to look for hepatitis A infection in a patient with atypical clinical picture causing a widespread systemic inflammatory response. Treatment with prednisone may result in resolution.http://dx.doi.org/10.1155/2014/286914
spellingShingle Geetika Bhatt
Varrinder S. Sandhu
Charlene K. Mitchell
A Rare Presentation of Hepatitis A Infection with Extrahepatic Manifestations
Case Reports in Gastrointestinal Medicine
title A Rare Presentation of Hepatitis A Infection with Extrahepatic Manifestations
title_full A Rare Presentation of Hepatitis A Infection with Extrahepatic Manifestations
title_fullStr A Rare Presentation of Hepatitis A Infection with Extrahepatic Manifestations
title_full_unstemmed A Rare Presentation of Hepatitis A Infection with Extrahepatic Manifestations
title_short A Rare Presentation of Hepatitis A Infection with Extrahepatic Manifestations
title_sort rare presentation of hepatitis a infection with extrahepatic manifestations
url http://dx.doi.org/10.1155/2014/286914
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