Impaired myofibroblast proliferation is a central feature of pathologic post-natal alveolar simplification

Impaired myofibroblast proliferation is a central feature of pathologic post-natal alveolar simplification

Premature infants with bronchopulmonary dysplasia (BPD) have impaired alveolar gas exchange due to alveolar simplification and dysmorphic pulmonary vasculature. Advances in clinical care have improved survival for infants with BPD, but the overall incidence of BPD remains unchanged because we lack s...

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Bibliographic Details
Main Authors: Imran S Khan, Christopher Molina, Xin Ren, Vincent C Auyeung, Max Cohen, Tatsuya Tsukui, Amha Atakilit, Dean Sheppard
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
myofibroblast
bronchopulmonary dysplasia
hyperoxia
lung development
Online Access:https://elifesciences.org/articles/94425
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https://elifesciences.org/articles/94425

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