A Novel Index for Prompt Prediction of Severity in Patients with Unstable Angina Pectoris

Objectives. Rapid risk stratification by emergency department (ED) physicians to evaluate patients with chest pain for predicting the short-term occurrence of major adverse cardiac event (MACE) is crucial. The aim of this study was to investigate the predictive value of platelet-lymphocyte ratio (PL...

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Main Authors: Mustafa Bolatkale, Ahmet Cagdas Acara
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Emergency Medicine International
Online Access:http://dx.doi.org/10.1155/2020/7651610
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author Mustafa Bolatkale
Ahmet Cagdas Acara
author_facet Mustafa Bolatkale
Ahmet Cagdas Acara
author_sort Mustafa Bolatkale
collection DOAJ
description Objectives. Rapid risk stratification by emergency department (ED) physicians to evaluate patients with chest pain for predicting the short-term occurrence of major adverse cardiac event (MACE) is crucial. The aim of this study was to investigate the predictive value of platelet-lymphocyte ratio (PLR) levels and compare with the modified heart score (m-HS) and stress testing to predict the severity of high-risk patients with unstable angina pectoris (UAP) in the ED. Methods. This study is prospective which included 316 patients with UAP and 316 control healthy subjects. The study took place from 01 April 2016, until 01 April 2017, in Medipol University. Result. The mean PLR levels in the UAP group were higher than those in the control group (p<0.001). The mean PLR of the m-HS ≥4 group was higher than that in the m-HS ≤3 group (p<0.001). The mean levels of PLR in the subgroups based on the stress testing positivity were higher than those in the stress testing negative subgroup (p<0.001). PLR levels were positively correlated with the m-HS, stress testing, and treatment decision in this study (r = 0.559; p<0.001; r = 0.582; p<0.001; r = 0.789; p<0.001, respectively). Conclusion. A positive correlation was determined with an increase in m-HS, treatment decision, and positive exercise testing as the PLR levels increased, indicating the severity of high risk of UAP in the ED.
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spelling doaj-art-77b6bb818375405abbdd84a9fa2e6c072025-02-03T01:28:21ZengWileyEmergency Medicine International2090-28402090-28592020-01-01202010.1155/2020/76516107651610A Novel Index for Prompt Prediction of Severity in Patients with Unstable Angina PectorisMustafa Bolatkale0Ahmet Cagdas Acara1Medipol University Hospital, Department of Emergency Medicine, Istanbul, TurkeyBozyaka Research and Training Hospital, Department of Emergency Medicine, Izmir, TurkeyObjectives. Rapid risk stratification by emergency department (ED) physicians to evaluate patients with chest pain for predicting the short-term occurrence of major adverse cardiac event (MACE) is crucial. The aim of this study was to investigate the predictive value of platelet-lymphocyte ratio (PLR) levels and compare with the modified heart score (m-HS) and stress testing to predict the severity of high-risk patients with unstable angina pectoris (UAP) in the ED. Methods. This study is prospective which included 316 patients with UAP and 316 control healthy subjects. The study took place from 01 April 2016, until 01 April 2017, in Medipol University. Result. The mean PLR levels in the UAP group were higher than those in the control group (p<0.001). The mean PLR of the m-HS ≥4 group was higher than that in the m-HS ≤3 group (p<0.001). The mean levels of PLR in the subgroups based on the stress testing positivity were higher than those in the stress testing negative subgroup (p<0.001). PLR levels were positively correlated with the m-HS, stress testing, and treatment decision in this study (r = 0.559; p<0.001; r = 0.582; p<0.001; r = 0.789; p<0.001, respectively). Conclusion. A positive correlation was determined with an increase in m-HS, treatment decision, and positive exercise testing as the PLR levels increased, indicating the severity of high risk of UAP in the ED.http://dx.doi.org/10.1155/2020/7651610
spellingShingle Mustafa Bolatkale
Ahmet Cagdas Acara
A Novel Index for Prompt Prediction of Severity in Patients with Unstable Angina Pectoris
Emergency Medicine International
title A Novel Index for Prompt Prediction of Severity in Patients with Unstable Angina Pectoris
title_full A Novel Index for Prompt Prediction of Severity in Patients with Unstable Angina Pectoris
title_fullStr A Novel Index for Prompt Prediction of Severity in Patients with Unstable Angina Pectoris
title_full_unstemmed A Novel Index for Prompt Prediction of Severity in Patients with Unstable Angina Pectoris
title_short A Novel Index for Prompt Prediction of Severity in Patients with Unstable Angina Pectoris
title_sort novel index for prompt prediction of severity in patients with unstable angina pectoris
url http://dx.doi.org/10.1155/2020/7651610
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