Partial Nephrectomy for a Massive Sporadic Renal Angiomyolipoma: Case Report and Review of the Literature
Introduction. Angiomyolipomas are the most common benign tumor of the kidney, associated with Tuberous Sclerosis in 20% of cases and arising sporadically in 80% of cases. Renal angiomyolipomas are neoplasms of mesenchymal origin with varying proportions of vasculature, smooth muscle spindle cells, a...
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Wiley
2016-01-01
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| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2016/3420741 |
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| author | Jacob Albersheim-Carter Molly Klein Paari Murugan Christopher J. Weight |
| author_facet | Jacob Albersheim-Carter Molly Klein Paari Murugan Christopher J. Weight |
| author_sort | Jacob Albersheim-Carter |
| collection | DOAJ |
| description | Introduction. Angiomyolipomas are the most common benign tumor of the kidney, associated with Tuberous Sclerosis in 20% of cases and arising sporadically in 80% of cases. Renal angiomyolipomas are neoplasms of mesenchymal origin with varying proportions of vasculature, smooth muscle spindle cells, and adipocytes, making management of such neoplasms a challenging endeavor. Possible management options include partial or radical nephrectomy and segmental renal artery embolization. Case Presentation. A 61-year-old woman admitted for a large retroperitoneal hemorrhage was discovered to have a giant, sporadic, 3818.3 g, 30.0 × 26.5 × 18.0 cm left perinephric angiomyolipoma. Given her hemodynamic instability upon presentation, she underwent segmental arterial embolization, followed by an open left partial nephrectomy. Ten-month follow-up revealed no noticeable loss of renal function. Discussion. Literature review revealed occasional renal angiomyolipomas of comparable size, with all angiomyolipomas larger than this requiring treatment with radical nephrectomy. Conclusion. We show that nephron-sparing surgery may be considered in the treatment of even the largest of renal angiomyolipomas. |
| format | Article |
| id | doaj-art-77a8f9bd1e7d417db8976f7071badb33 |
| institution | Kabale University |
| issn | 2090-696X 2090-6978 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Urology |
| spelling | doaj-art-77a8f9bd1e7d417db8976f7071badb332025-02-03T01:09:00ZengWileyCase Reports in Urology2090-696X2090-69782016-01-01201610.1155/2016/34207413420741Partial Nephrectomy for a Massive Sporadic Renal Angiomyolipoma: Case Report and Review of the LiteratureJacob Albersheim-Carter0Molly Klein1Paari Murugan2Christopher J. Weight3University of Minnesota Medical School, Minneapolis, MN, USAUniversity of Minnesota Medical School, Minneapolis, MN, USAUniversity of Minnesota Medical School, Minneapolis, MN, USAUniversity of Minnesota Medical School, Minneapolis, MN, USAIntroduction. Angiomyolipomas are the most common benign tumor of the kidney, associated with Tuberous Sclerosis in 20% of cases and arising sporadically in 80% of cases. Renal angiomyolipomas are neoplasms of mesenchymal origin with varying proportions of vasculature, smooth muscle spindle cells, and adipocytes, making management of such neoplasms a challenging endeavor. Possible management options include partial or radical nephrectomy and segmental renal artery embolization. Case Presentation. A 61-year-old woman admitted for a large retroperitoneal hemorrhage was discovered to have a giant, sporadic, 3818.3 g, 30.0 × 26.5 × 18.0 cm left perinephric angiomyolipoma. Given her hemodynamic instability upon presentation, she underwent segmental arterial embolization, followed by an open left partial nephrectomy. Ten-month follow-up revealed no noticeable loss of renal function. Discussion. Literature review revealed occasional renal angiomyolipomas of comparable size, with all angiomyolipomas larger than this requiring treatment with radical nephrectomy. Conclusion. We show that nephron-sparing surgery may be considered in the treatment of even the largest of renal angiomyolipomas.http://dx.doi.org/10.1155/2016/3420741 |
| spellingShingle | Jacob Albersheim-Carter Molly Klein Paari Murugan Christopher J. Weight Partial Nephrectomy for a Massive Sporadic Renal Angiomyolipoma: Case Report and Review of the Literature Case Reports in Urology |
| title | Partial Nephrectomy for a Massive Sporadic Renal Angiomyolipoma: Case Report and Review of the Literature |
| title_full | Partial Nephrectomy for a Massive Sporadic Renal Angiomyolipoma: Case Report and Review of the Literature |
| title_fullStr | Partial Nephrectomy for a Massive Sporadic Renal Angiomyolipoma: Case Report and Review of the Literature |
| title_full_unstemmed | Partial Nephrectomy for a Massive Sporadic Renal Angiomyolipoma: Case Report and Review of the Literature |
| title_short | Partial Nephrectomy for a Massive Sporadic Renal Angiomyolipoma: Case Report and Review of the Literature |
| title_sort | partial nephrectomy for a massive sporadic renal angiomyolipoma case report and review of the literature |
| url | http://dx.doi.org/10.1155/2016/3420741 |
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