Neuroophthalmic Manifestations of Intracranial Tumours in Children
Background. All children between 0 and 16 years presenting with brain tumours confirmed by Magnetic Resonance Imaging (MRI) and treated surgically in our institute were included in this study. Objective. The aim of this study is to evaluate the neuroophthalmic and clinical characteristics of intracr...
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| Format: | Article |
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Wiley
2021-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/7793382 |
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| author | Megha Kotecha Sarang Gotecha Ashish Chugh Prashant Punia |
| author_facet | Megha Kotecha Sarang Gotecha Ashish Chugh Prashant Punia |
| author_sort | Megha Kotecha |
| collection | DOAJ |
| description | Background. All children between 0 and 16 years presenting with brain tumours confirmed by Magnetic Resonance Imaging (MRI) and treated surgically in our institute were included in this study. Objective. The aim of this study is to evaluate the neuroophthalmic and clinical characteristics of intracranial space occupying lesions in children. Methods. Neuroophthalmic manifestations along with location of the tumour by contrast-enhanced MRI, type of surgical intervention, and postoperative histopathological diagnosis were evaluated. Results. In pediatric brain tumours, male preponderance was seen and supratentorial location was more common in general, while in older children, infratentorial tumours were more common than supratentorial tumours. Headache, vomiting, and cerebellar signs were the commonest neurological features. Diminution of vision, diplopia, and strabismus were the commonest ophthalmic symptoms. Papilledema, ophthalmoparesis, and nystagmus were the most frequent ophthalmological signs. Neurological manifestations of seizures, altered sensorium and motor deficits were more frequently seen in supratentorial tumours, while cranial nerve involvement and ataxia were seen in infratentorial tumours. Ophthalmological manifestations including diplopia, strabismus, ophthalmoparesis, and nystagmus were more frequently seen in infratentorial tumours. Astrocytoma was the most frequent histopathological diagnosis followed by medulloblastoma. Conclusion. Diagnosis of pediatric intracranial tumours is complex and requires a multidisciplinary approach for prompt management. An ophthalmologist should have a high index of suspicion for brain tumours especially in patients presenting with common ocular symptoms like diminution of vision, diplopia, and strabismus without any neurological symptoms. |
| format | Article |
| id | doaj-art-77930bd23f1f438a8723e93bfad17067 |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-77930bd23f1f438a8723e93bfad170672025-02-03T01:28:14ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302021-01-01202110.1155/2021/77933827793382Neuroophthalmic Manifestations of Intracranial Tumours in ChildrenMegha Kotecha0Sarang Gotecha1Ashish Chugh2Prashant Punia3Department of Ophthalmology, Dr. D.Y. Patil Medical College and Hospital, Pimpri, Pune, Maharashtra, IndiaDepartment of Neurosurgery, Dr. D.Y. Patil Medical College and Hospital, Pimpri, Pune, Maharashtra, IndiaDepartment of Neurosurgery, Dr. D.Y. Patil Medical College and Hospital, Pimpri, Pune, Maharashtra, IndiaDepartment of Neurosurgery, Dr. D.Y. Patil Medical College and Hospital, Pimpri, Pune, Maharashtra, IndiaBackground. All children between 0 and 16 years presenting with brain tumours confirmed by Magnetic Resonance Imaging (MRI) and treated surgically in our institute were included in this study. Objective. The aim of this study is to evaluate the neuroophthalmic and clinical characteristics of intracranial space occupying lesions in children. Methods. Neuroophthalmic manifestations along with location of the tumour by contrast-enhanced MRI, type of surgical intervention, and postoperative histopathological diagnosis were evaluated. Results. In pediatric brain tumours, male preponderance was seen and supratentorial location was more common in general, while in older children, infratentorial tumours were more common than supratentorial tumours. Headache, vomiting, and cerebellar signs were the commonest neurological features. Diminution of vision, diplopia, and strabismus were the commonest ophthalmic symptoms. Papilledema, ophthalmoparesis, and nystagmus were the most frequent ophthalmological signs. Neurological manifestations of seizures, altered sensorium and motor deficits were more frequently seen in supratentorial tumours, while cranial nerve involvement and ataxia were seen in infratentorial tumours. Ophthalmological manifestations including diplopia, strabismus, ophthalmoparesis, and nystagmus were more frequently seen in infratentorial tumours. Astrocytoma was the most frequent histopathological diagnosis followed by medulloblastoma. Conclusion. Diagnosis of pediatric intracranial tumours is complex and requires a multidisciplinary approach for prompt management. An ophthalmologist should have a high index of suspicion for brain tumours especially in patients presenting with common ocular symptoms like diminution of vision, diplopia, and strabismus without any neurological symptoms.http://dx.doi.org/10.1155/2021/7793382 |
| spellingShingle | Megha Kotecha Sarang Gotecha Ashish Chugh Prashant Punia Neuroophthalmic Manifestations of Intracranial Tumours in Children Case Reports in Ophthalmological Medicine |
| title | Neuroophthalmic Manifestations of Intracranial Tumours in Children |
| title_full | Neuroophthalmic Manifestations of Intracranial Tumours in Children |
| title_fullStr | Neuroophthalmic Manifestations of Intracranial Tumours in Children |
| title_full_unstemmed | Neuroophthalmic Manifestations of Intracranial Tumours in Children |
| title_short | Neuroophthalmic Manifestations of Intracranial Tumours in Children |
| title_sort | neuroophthalmic manifestations of intracranial tumours in children |
| url | http://dx.doi.org/10.1155/2021/7793382 |
| work_keys_str_mv | AT meghakotecha neuroophthalmicmanifestationsofintracranialtumoursinchildren AT saranggotecha neuroophthalmicmanifestationsofintracranialtumoursinchildren AT ashishchugh neuroophthalmicmanifestationsofintracranialtumoursinchildren AT prashantpunia neuroophthalmicmanifestationsofintracranialtumoursinchildren |