Three-Year Point Prevalence Survey of Antimicrobial Use in a Chinese University Hospital
To evaluate the prevalence and quality of antimicrobial prescriptions using a Global Point Prevalence Survey (PPS) tool and help identify targets for improvement of antimicrobial prescribing and inform the development of antimicrobial stewardship activities. Antimicrobial prescriptions for inpatient...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2024/6698387 |
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| author | Fa-Hong Jing Qiang Wang Tian-Jiao He Na Xin Yao-Wei Wang Yang Han Xin Wang Zhuo Li |
| author_facet | Fa-Hong Jing Qiang Wang Tian-Jiao He Na Xin Yao-Wei Wang Yang Han Xin Wang Zhuo Li |
| author_sort | Fa-Hong Jing |
| collection | DOAJ |
| description | To evaluate the prevalence and quality of antimicrobial prescriptions using a Global Point Prevalence Survey (PPS) tool and help identify targets for improvement of antimicrobial prescribing and inform the development of antimicrobial stewardship activities. Antimicrobial prescriptions for inpatients staying at a hospital overnight were surveyed on one weekday in October 2018, November 2019, and November 2020. Data including basic patient information, antimicrobial drugs, quality evaluation of antimicrobial drug prescription, and the risk factors of nosocomial infection were collected from doctor network workstation. Patient information was anonymized and entered in the PPS Web application by physicians. A total of 720 patients (median age, 62 years) were surveyed. Of them, 246 (34.2%) were prescribed antimicrobials on the survey days. Hospital-wide antimicrobial use had a significantly decreasing trend (P<0.001). The most commonly prescribed antimicrobial drugs were third-generation cephalosporins (40.5%), followed by quinolones (21.8%) and second-generation cephalosporin (12.5%). In our study, cefoperazone/sulbactam, ceftazidime, and levofloxacin were the most commonly used antimicrobials. The most common indication for antimicrobial use was pneumonia or lower respiratory tract infection (159/321, 49.5%). Antimicrobial for surgical prophylaxis represented 16.2% of the total antibiotic doses. Of those, 67.3% were administered for more than 24 h. The rate of adherence to antibiotic guidelines was 61.4%. The indications for antimicrobials were not documented in 54.5% of the prescriptions. Stop/review date was documented for 36.8% of prescriptions. The PPS tool is useful in identifying targets to enhance the quality of antimicrobial prescriptions to improve the adherence rate in hospitals. This survey can be used as a control to assess the rational application quality of antimicrobial after regular application of antimicrobial intervention. |
| format | Article |
| id | doaj-art-778ccc4c50c44736a92b85d791dc7270 |
| institution | Kabale University |
| issn | 1918-1493 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-778ccc4c50c44736a92b85d791dc72702025-02-03T01:32:00ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1918-14932024-01-01202410.1155/2024/6698387Three-Year Point Prevalence Survey of Antimicrobial Use in a Chinese University HospitalFa-Hong Jing0Qiang Wang1Tian-Jiao He2Na Xin3Yao-Wei Wang4Yang Han5Xin Wang6Zhuo Li7Department of Laboratory MedicineDepartment of Infection ManagementDepartment of Laboratory MedicineDepartment of Laboratory MedicineDepartment of Laboratory MedicineDepartment of Laboratory MedicineDepartment of Laboratory MedicineDepartment of Laboratory MedicineTo evaluate the prevalence and quality of antimicrobial prescriptions using a Global Point Prevalence Survey (PPS) tool and help identify targets for improvement of antimicrobial prescribing and inform the development of antimicrobial stewardship activities. Antimicrobial prescriptions for inpatients staying at a hospital overnight were surveyed on one weekday in October 2018, November 2019, and November 2020. Data including basic patient information, antimicrobial drugs, quality evaluation of antimicrobial drug prescription, and the risk factors of nosocomial infection were collected from doctor network workstation. Patient information was anonymized and entered in the PPS Web application by physicians. A total of 720 patients (median age, 62 years) were surveyed. Of them, 246 (34.2%) were prescribed antimicrobials on the survey days. Hospital-wide antimicrobial use had a significantly decreasing trend (P<0.001). The most commonly prescribed antimicrobial drugs were third-generation cephalosporins (40.5%), followed by quinolones (21.8%) and second-generation cephalosporin (12.5%). In our study, cefoperazone/sulbactam, ceftazidime, and levofloxacin were the most commonly used antimicrobials. The most common indication for antimicrobial use was pneumonia or lower respiratory tract infection (159/321, 49.5%). Antimicrobial for surgical prophylaxis represented 16.2% of the total antibiotic doses. Of those, 67.3% were administered for more than 24 h. The rate of adherence to antibiotic guidelines was 61.4%. The indications for antimicrobials were not documented in 54.5% of the prescriptions. Stop/review date was documented for 36.8% of prescriptions. The PPS tool is useful in identifying targets to enhance the quality of antimicrobial prescriptions to improve the adherence rate in hospitals. This survey can be used as a control to assess the rational application quality of antimicrobial after regular application of antimicrobial intervention.http://dx.doi.org/10.1155/2024/6698387 |
| spellingShingle | Fa-Hong Jing Qiang Wang Tian-Jiao He Na Xin Yao-Wei Wang Yang Han Xin Wang Zhuo Li Three-Year Point Prevalence Survey of Antimicrobial Use in a Chinese University Hospital Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Three-Year Point Prevalence Survey of Antimicrobial Use in a Chinese University Hospital |
| title_full | Three-Year Point Prevalence Survey of Antimicrobial Use in a Chinese University Hospital |
| title_fullStr | Three-Year Point Prevalence Survey of Antimicrobial Use in a Chinese University Hospital |
| title_full_unstemmed | Three-Year Point Prevalence Survey of Antimicrobial Use in a Chinese University Hospital |
| title_short | Three-Year Point Prevalence Survey of Antimicrobial Use in a Chinese University Hospital |
| title_sort | three year point prevalence survey of antimicrobial use in a chinese university hospital |
| url | http://dx.doi.org/10.1155/2024/6698387 |
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