Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should Know
This paper presents to the surgical community an unusual and often ignored cause of gastrointestinal bleeding. Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis (HLH) is a rare medical entity characterized by phagocytosis of red blood cells, leucocytes, platelets, and their precursors in...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2015/745848 |
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| _version_ | 1832551814395854848 |
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| author | S. Popeskou M. Gavillet N. Demartines D. Christoforidis |
| author_facet | S. Popeskou M. Gavillet N. Demartines D. Christoforidis |
| author_sort | S. Popeskou |
| collection | DOAJ |
| description | This paper presents to the surgical community an unusual and often ignored cause of gastrointestinal bleeding. Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis (HLH) is a rare medical entity characterized by phagocytosis of red blood cells, leucocytes, platelets, and their precursors in the bone marrow by activated macrophages. When intestinal bleeding is present, the management is very challenging with extremely high mortality rates. Early diagnosis and treatment seem to be the most important factors for a successful outcome. We present two cases and review another 18 from the literature. |
| format | Article |
| id | doaj-art-777221183bc74f6c86be3a3f70d747d6 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-777221183bc74f6c86be3a3f70d747d62025-02-03T06:00:31ZengWileyCase Reports in Surgery2090-69002090-69192015-01-01201510.1155/2015/745848745848Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should KnowS. Popeskou0M. Gavillet1N. Demartines2D. Christoforidis3Department of Surgery, Lugano Regional Hospital, SwitzerlandDepartment of Hematology, University Hospital of Lausanne, SwitzerlandDepartment of Surgery, University Hospital of Lausanne, SwitzerlandDepartment of Surgery, Lugano Regional Hospital, SwitzerlandThis paper presents to the surgical community an unusual and often ignored cause of gastrointestinal bleeding. Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis (HLH) is a rare medical entity characterized by phagocytosis of red blood cells, leucocytes, platelets, and their precursors in the bone marrow by activated macrophages. When intestinal bleeding is present, the management is very challenging with extremely high mortality rates. Early diagnosis and treatment seem to be the most important factors for a successful outcome. We present two cases and review another 18 from the literature.http://dx.doi.org/10.1155/2015/745848 |
| spellingShingle | S. Popeskou M. Gavillet N. Demartines D. Christoforidis Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should Know Case Reports in Surgery |
| title | Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should Know |
| title_full | Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should Know |
| title_fullStr | Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should Know |
| title_full_unstemmed | Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should Know |
| title_short | Hemophagocytic Lymphohistiocytosis and Gastrointestinal Bleeding: What a Surgeon Should Know |
| title_sort | hemophagocytic lymphohistiocytosis and gastrointestinal bleeding what a surgeon should know |
| url | http://dx.doi.org/10.1155/2015/745848 |
| work_keys_str_mv | AT spopeskou hemophagocyticlymphohistiocytosisandgastrointestinalbleedingwhatasurgeonshouldknow AT mgavillet hemophagocyticlymphohistiocytosisandgastrointestinalbleedingwhatasurgeonshouldknow AT ndemartines hemophagocyticlymphohistiocytosisandgastrointestinalbleedingwhatasurgeonshouldknow AT dchristoforidis hemophagocyticlymphohistiocytosisandgastrointestinalbleedingwhatasurgeonshouldknow |