Contrast Sensitivity of Thyroid Associated Ophthalmopathy Patients without Obvious Optic Neuropathy

Purpose. To compare the contrast sensitivity levels of thyroid associated ophthalmopathy (TAO) patients without obvious optic neuropathy with those of healthy people. Methods. Forty eyes of 20 TAO patients without dysthyroid optic neuropathy and 40 eyes of 20 healthy subjects were evaluated in this...

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Main Authors: Ümit Beden, Sümeyra Kaya, Volkan Yeter, Dilek Erkan
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2013/943789
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author Ümit Beden
Sümeyra Kaya
Volkan Yeter
Dilek Erkan
author_facet Ümit Beden
Sümeyra Kaya
Volkan Yeter
Dilek Erkan
author_sort Ümit Beden
collection DOAJ
description Purpose. To compare the contrast sensitivity levels of thyroid associated ophthalmopathy (TAO) patients without obvious optic neuropathy with those of healthy people. Methods. Forty eyes of 20 TAO patients without dysthyroid optic neuropathy and 40 eyes of 20 healthy subjects were evaluated in this prospective case-controlled study. The contrast sensitivity functions (CSFs) of all subjects were measured by the functional acuity contrast test (FACT) in five frequencies which were 1,5 cpd (A), 3 cpd (B), 6 cpd (C), 12 cpd (D), and 18 cpd (E). Results were compared for both groups, and a correlation of CSF with Hertel and clinical activity scores was assessed. Results. There was no statistically significant difference between TAO patients and control groups for age and sex. TAO patients had lower levels than the control group in all the frequencies of CSFs (P<0.05) and the difference in contrast sensitivity functions between the groups seems to be more significant in higher frequencies (B, C, D, and E) (P<0.001). Conclusions. TAO patients without DON can have contrast sensitivity loss and this would probably imply subtle optic nerve dysfunction in early disease phase.
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spelling doaj-art-776187f9113041dcbf56fd2ee6704db32025-02-03T06:11:01ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/943789943789Contrast Sensitivity of Thyroid Associated Ophthalmopathy Patients without Obvious Optic NeuropathyÜmit Beden0Sümeyra Kaya1Volkan Yeter2Dilek Erkan3Department of Ophthalmology, Memorial Hospital, Istanbul, TurkeyDepartment of Ophthalmology, Ahi Evran University, Kırşehir, TurkeyDepartment of Ophthalmology, Erzincan University, Mengücek Gazi Training and Research Hospital, Göz Hastalıkları, 24000 Erzincan, TurkeyDepartment of Ophthalmology, Dünya Göz Hospital, Samsun, TurkeyPurpose. To compare the contrast sensitivity levels of thyroid associated ophthalmopathy (TAO) patients without obvious optic neuropathy with those of healthy people. Methods. Forty eyes of 20 TAO patients without dysthyroid optic neuropathy and 40 eyes of 20 healthy subjects were evaluated in this prospective case-controlled study. The contrast sensitivity functions (CSFs) of all subjects were measured by the functional acuity contrast test (FACT) in five frequencies which were 1,5 cpd (A), 3 cpd (B), 6 cpd (C), 12 cpd (D), and 18 cpd (E). Results were compared for both groups, and a correlation of CSF with Hertel and clinical activity scores was assessed. Results. There was no statistically significant difference between TAO patients and control groups for age and sex. TAO patients had lower levels than the control group in all the frequencies of CSFs (P<0.05) and the difference in contrast sensitivity functions between the groups seems to be more significant in higher frequencies (B, C, D, and E) (P<0.001). Conclusions. TAO patients without DON can have contrast sensitivity loss and this would probably imply subtle optic nerve dysfunction in early disease phase.http://dx.doi.org/10.1155/2013/943789
spellingShingle Ümit Beden
Sümeyra Kaya
Volkan Yeter
Dilek Erkan
Contrast Sensitivity of Thyroid Associated Ophthalmopathy Patients without Obvious Optic Neuropathy
The Scientific World Journal
title Contrast Sensitivity of Thyroid Associated Ophthalmopathy Patients without Obvious Optic Neuropathy
title_full Contrast Sensitivity of Thyroid Associated Ophthalmopathy Patients without Obvious Optic Neuropathy
title_fullStr Contrast Sensitivity of Thyroid Associated Ophthalmopathy Patients without Obvious Optic Neuropathy
title_full_unstemmed Contrast Sensitivity of Thyroid Associated Ophthalmopathy Patients without Obvious Optic Neuropathy
title_short Contrast Sensitivity of Thyroid Associated Ophthalmopathy Patients without Obvious Optic Neuropathy
title_sort contrast sensitivity of thyroid associated ophthalmopathy patients without obvious optic neuropathy
url http://dx.doi.org/10.1155/2013/943789
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AT volkanyeter contrastsensitivityofthyroidassociatedophthalmopathypatientswithoutobviousopticneuropathy
AT dilekerkan contrastsensitivityofthyroidassociatedophthalmopathypatientswithoutobviousopticneuropathy