Acetylation of E2F1 at K125 facilitates cell apoptosis under serum stress

Acetylation of E2F1 at K125 facilitates cell apoptosis under serum stress

E2F1 is a critical transcription factor that regulates cell cycle progression, is expressed at high levels in most cancer cells, and activates the biogenesis of proteins related to the cell cycle. Over recent years, researchers have demonstrated that E2F1 could also facilitate cellular apoptosis und...

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Bibliographic Details
Main Authors: Zejun Fang, Chaoju Gong, Yanyan Hu, Tingting Cui, Min Lin, Sha Lin, Ming Ye
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Translational Oncology
Subjects:
Hepatocellular carcinoma
E2F1
HDAC5
Cell apoptosis
Serum stress
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324003851
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