Discontinuation of anti-seizure therapy in epilepsy patients
Currently, among one of the most important issues in epileptology is discontinuation of anti-seizure therapy in patients with epilepsy. The article presents contemporary approaches to solving the problem of discontinuation of antiepileptic drugs (AEDs) in patients with epilepsy based on assessing Ru...
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| Format: | Article |
| Language: | Russian |
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IRBIS LLC
2025-05-01
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| Series: | Эпилепсия и пароксизмальные состояния |
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| Online Access: | https://www.epilepsia.su/jour/article/view/1191 |
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| _version_ | 1849395648712933376 |
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| author | O. A. Milovanova M. B. Mironov E. A. Sandu |
| author_facet | O. A. Milovanova M. B. Mironov E. A. Sandu |
| author_sort | O. A. Milovanova |
| collection | DOAJ |
| description | Currently, among one of the most important issues in epileptology is discontinuation of anti-seizure therapy in patients with epilepsy. The article presents contemporary approaches to solving the problem of discontinuation of antiepileptic drugs (AEDs) in patients with epilepsy based on assessing Russian and foreign publications, as well as our clinical experience. A comprehensive analysis of high-priority medical sources on AED discontinuation was carried out, including recommendations proposed by the Italian League Against Epilepsy (2013), practical recommendations for adults and children released by the American Academy of Neurology (2021) currently referenced on the official International League Against Epilepsy website, as well as recommendations of the Russian League Against Epilepsy (2022). A fundamentally crucial point in all the recommendations presented above is the lack of strict time frames, and that all provisions can be discussed with a patient and patient’s relatives. It is emphasized that a high quality of life of a patient with epilepsy is achieved only in the absence of epileptic seizures. In this regard, it seems extremely important to apply an individual approach to AED discontinuation, depending on preferences specified by a patient and patient’ family. All aspects related to AED discontinuation should be discussed by neurologists (epileptologists) in collaboration with lawyers, patient family members and various community representatives, not forgetting about the medical-social, medical-legal and ethical issues that arise upon AED discontinuation as well as decision-making on removing the diagnosis of epilepsy. |
| format | Article |
| id | doaj-art-7722e6c0325f4d419dae40ff8f5eab8b |
| institution | Kabale University |
| issn | 2077-8333 2311-4088 |
| language | Russian |
| publishDate | 2025-05-01 |
| publisher | IRBIS LLC |
| record_format | Article |
| series | Эпилепсия и пароксизмальные состояния |
| spelling | doaj-art-7722e6c0325f4d419dae40ff8f5eab8b2025-08-20T03:39:32ZrusIRBIS LLCЭпилепсия и пароксизмальные состояния2077-83332311-40882025-05-011719410010.17749/2077-8333/epi.par.con.2025.227678Discontinuation of anti-seizure therapy in epilepsy patientsO. A. Milovanova0M. B. Mironov1E. A. Sandu2Russian Medical Academy of Continuous Professional Education ; Bashlyaeva Children's City Clinical HospitalBashlyaeva Children's City Clinical Hospital ; Center for Neurology and PediatricsUniversity Clinical Hospital No. 5, Sechenov University ; Istok Clinic LLCCurrently, among one of the most important issues in epileptology is discontinuation of anti-seizure therapy in patients with epilepsy. The article presents contemporary approaches to solving the problem of discontinuation of antiepileptic drugs (AEDs) in patients with epilepsy based on assessing Russian and foreign publications, as well as our clinical experience. A comprehensive analysis of high-priority medical sources on AED discontinuation was carried out, including recommendations proposed by the Italian League Against Epilepsy (2013), practical recommendations for adults and children released by the American Academy of Neurology (2021) currently referenced on the official International League Against Epilepsy website, as well as recommendations of the Russian League Against Epilepsy (2022). A fundamentally crucial point in all the recommendations presented above is the lack of strict time frames, and that all provisions can be discussed with a patient and patient’s relatives. It is emphasized that a high quality of life of a patient with epilepsy is achieved only in the absence of epileptic seizures. In this regard, it seems extremely important to apply an individual approach to AED discontinuation, depending on preferences specified by a patient and patient’ family. All aspects related to AED discontinuation should be discussed by neurologists (epileptologists) in collaboration with lawyers, patient family members and various community representatives, not forgetting about the medical-social, medical-legal and ethical issues that arise upon AED discontinuation as well as decision-making on removing the diagnosis of epilepsy.https://www.epilepsia.su/jour/article/view/1191epilepsyanticonvulsant therapyantiepileptic drugsdiscontinuationrecommendations |
| spellingShingle | O. A. Milovanova M. B. Mironov E. A. Sandu Discontinuation of anti-seizure therapy in epilepsy patients Эпилепсия и пароксизмальные состояния epilepsy anticonvulsant therapy antiepileptic drugs discontinuation recommendations |
| title | Discontinuation of anti-seizure therapy in epilepsy patients |
| title_full | Discontinuation of anti-seizure therapy in epilepsy patients |
| title_fullStr | Discontinuation of anti-seizure therapy in epilepsy patients |
| title_full_unstemmed | Discontinuation of anti-seizure therapy in epilepsy patients |
| title_short | Discontinuation of anti-seizure therapy in epilepsy patients |
| title_sort | discontinuation of anti seizure therapy in epilepsy patients |
| topic | epilepsy anticonvulsant therapy antiepileptic drugs discontinuation recommendations |
| url | https://www.epilepsia.su/jour/article/view/1191 |
| work_keys_str_mv | AT oamilovanova discontinuationofantiseizuretherapyinepilepsypatients AT mbmironov discontinuationofantiseizuretherapyinepilepsypatients AT easandu discontinuationofantiseizuretherapyinepilepsypatients |