Exploring the potential of an oyster (Saccostrea mordax) in oligotrophic seas: Effects of starvation on physiological and molecular regulation
Starvation is the most common physiological challenge for marine bivalves, especially in oligotrophic seas like the South China Sea. Its dominant oyster species, Saccostrea mordax, remains unclear regarding starvation tolerance and underlying mechanisms. Here, we treated S. mordax with starvation fo...
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Elsevier
2025-03-01
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| Series: | Aquaculture Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352513424006616 |
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| author | Shuming Guo Liqiang Zhao Yuexin Zhao Zohaib Noor Xiaogang Yang Shiwei Fu Zhen Zhao Weitao Wan Jinkuan Wei Yanping Qin Haitao Ma Ziniu Yu Jun Li Yuehuan Zhang |
| author_facet | Shuming Guo Liqiang Zhao Yuexin Zhao Zohaib Noor Xiaogang Yang Shiwei Fu Zhen Zhao Weitao Wan Jinkuan Wei Yanping Qin Haitao Ma Ziniu Yu Jun Li Yuehuan Zhang |
| author_sort | Shuming Guo |
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| description | Starvation is the most common physiological challenge for marine bivalves, especially in oligotrophic seas like the South China Sea. Its dominant oyster species, Saccostrea mordax, remains unclear regarding starvation tolerance and underlying mechanisms. Here, we treated S. mordax with starvation for four months. Compared with the control group, no significant decrease in survival was observed in starvation-treated S. mordax. A significant decrease in oyster respiration rate was observed from the 14th day, and on the 90th day, the activities of Superoxide dismutase (SOD) and Catalase (CAT), and the content of Malondialdehyde (MDA) in the gill of oyster decreased. Besides, we found that oysters had a slow process of morphological deterioration in different tissues (gill, digestive gland, muscle) under starvation treatment. The integration of transcriptomics analyses indicates that the metabolic capacity of oysters decreases under prolonged starvation, and the expression of genes in the solute carrier family that contribute to nutrient transport was down-regulated. Moreover, the down-regulation of the expression of immune-related genes, such as the IAP gene family, MYD88, and CDC42, indicated that the homeostasis between apoptosis and cell proliferation was disrupted, which was in agreement with the results of sections with the enlarged lumen of the digestive gland and apoptosis of digestive cells. On the contrary, most genes in the collagen family, that contribute to the stability of tissue structure, were up-regulated, which may contribute to long-term tolerance to starvation. Overall, our study reveals the physiological responses and mechanisms of starvation tolerance in S. mordax, which has the potential to contribute to the restoration of island reefs in oligotrophic seas. |
| format | Article |
| id | doaj-art-771a4cf9ea8f4d50b85ccf4da11014cb |
| institution | Kabale University |
| issn | 2352-5134 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Aquaculture Reports |
| spelling | doaj-art-771a4cf9ea8f4d50b85ccf4da11014cb2025-02-06T05:12:11ZengElsevierAquaculture Reports2352-51342025-03-0140102573Exploring the potential of an oyster (Saccostrea mordax) in oligotrophic seas: Effects of starvation on physiological and molecular regulationShuming Guo0Liqiang Zhao1Yuexin Zhao2Zohaib Noor3Xiaogang Yang4Shiwei Fu5Zhen Zhao6Weitao Wan7Jinkuan Wei8Yanping Qin9Haitao Ma10Ziniu Yu11Jun Li12Yuehuan Zhang13Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; University of the Chinese Academy of Sciences, Beijing 100049, China; Guangdong Ocean University, Zhangjiang 524088, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, ChinaSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; Guangdong Ocean University, Zhangjiang 524088, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, ChinaDalian Ocean University, Dalian 116023, ChinaSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; University of the Chinese Academy of Sciences, Beijing 100049, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, ChinaSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, ChinaSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; University of the Chinese Academy of Sciences, Beijing 100049, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, ChinaSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, ChinaSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; University of the Chinese Academy of Sciences, Beijing 100049, China; Guangdong Ocean University, Zhangjiang 524088, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, ChinaSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, ChinaSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; Daya Bay Marine Biology Research Station, Chinese Academy of Sciences, Shenzhen 518124, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan 430072, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, ChinaSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; Daya Bay Marine Biology Research Station, Chinese Academy of Sciences, Shenzhen 518124, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan 430072, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, ChinaSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; Daya Bay Marine Biology Research Station, Chinese Academy of Sciences, Shenzhen 518124, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, ChinaSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; Daya Bay Marine Biology Research Station, Chinese Academy of Sciences, Shenzhen 518124, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan 430072, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, China; Correspondence to: South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519015, China; Daya Bay Marine Biology Research Station, Chinese Academy of Sciences, Shenzhen 518124, China; Hainan Provincial Key Laboratory of Tropical Marine Biology Technology, Sanya Marine Eco-environment Engineering Research Institute, Tropical Marine Biological Research Station in Hainan, Chinese Academy of Sciences, Sanya 572024, China; Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan 430072, China; CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Science, Guangzhou 510301, China; Correspondence to: South China Sea Institute of Oceanology, Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.Starvation is the most common physiological challenge for marine bivalves, especially in oligotrophic seas like the South China Sea. Its dominant oyster species, Saccostrea mordax, remains unclear regarding starvation tolerance and underlying mechanisms. Here, we treated S. mordax with starvation for four months. Compared with the control group, no significant decrease in survival was observed in starvation-treated S. mordax. A significant decrease in oyster respiration rate was observed from the 14th day, and on the 90th day, the activities of Superoxide dismutase (SOD) and Catalase (CAT), and the content of Malondialdehyde (MDA) in the gill of oyster decreased. Besides, we found that oysters had a slow process of morphological deterioration in different tissues (gill, digestive gland, muscle) under starvation treatment. The integration of transcriptomics analyses indicates that the metabolic capacity of oysters decreases under prolonged starvation, and the expression of genes in the solute carrier family that contribute to nutrient transport was down-regulated. Moreover, the down-regulation of the expression of immune-related genes, such as the IAP gene family, MYD88, and CDC42, indicated that the homeostasis between apoptosis and cell proliferation was disrupted, which was in agreement with the results of sections with the enlarged lumen of the digestive gland and apoptosis of digestive cells. On the contrary, most genes in the collagen family, that contribute to the stability of tissue structure, were up-regulated, which may contribute to long-term tolerance to starvation. Overall, our study reveals the physiological responses and mechanisms of starvation tolerance in S. mordax, which has the potential to contribute to the restoration of island reefs in oligotrophic seas.http://www.sciencedirect.com/science/article/pii/S2352513424006616Oligotrophic seaSaccostrea mordaxStarvation toleranceOyster reefTranscriptomics |
| spellingShingle | Shuming Guo Liqiang Zhao Yuexin Zhao Zohaib Noor Xiaogang Yang Shiwei Fu Zhen Zhao Weitao Wan Jinkuan Wei Yanping Qin Haitao Ma Ziniu Yu Jun Li Yuehuan Zhang Exploring the potential of an oyster (Saccostrea mordax) in oligotrophic seas: Effects of starvation on physiological and molecular regulation Aquaculture Reports Oligotrophic sea Saccostrea mordax Starvation tolerance Oyster reef Transcriptomics |
| title | Exploring the potential of an oyster (Saccostrea mordax) in oligotrophic seas: Effects of starvation on physiological and molecular regulation |
| title_full | Exploring the potential of an oyster (Saccostrea mordax) in oligotrophic seas: Effects of starvation on physiological and molecular regulation |
| title_fullStr | Exploring the potential of an oyster (Saccostrea mordax) in oligotrophic seas: Effects of starvation on physiological and molecular regulation |
| title_full_unstemmed | Exploring the potential of an oyster (Saccostrea mordax) in oligotrophic seas: Effects of starvation on physiological and molecular regulation |
| title_short | Exploring the potential of an oyster (Saccostrea mordax) in oligotrophic seas: Effects of starvation on physiological and molecular regulation |
| title_sort | exploring the potential of an oyster saccostrea mordax in oligotrophic seas effects of starvation on physiological and molecular regulation |
| topic | Oligotrophic sea Saccostrea mordax Starvation tolerance Oyster reef Transcriptomics |
| url | http://www.sciencedirect.com/science/article/pii/S2352513424006616 |
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