Hierarchical progressive learning for zero-shot peptide-HLA binding prediction and automated antigenic peptide design
Summary: Predicting the binding of peptides to human leukocyte antigen (HLA) alleles is critical for identifying epitopes initiating immune responses in vaccine development and immunotherapies. Despite the progress in predicting binding peptides of 1% HLA class-I alleles with in silico prediction to...
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| Main Authors: | Xinyuan Zhu, Jiadong Lu, Xinting Hu, Tengchuan Jin, Shan Lu, Fuli Feng |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
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| Series: | Cell Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124725005340 |
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