Distribution of cephalosporin-resistant Campylobacter species isolated from meat sold in Abakaliki, Nigeria

Background: Campylobacter species have been at the forefront of the field as etiologic agents of foodborne gastroenteritis. The importance of animal proteins, especially contaminated meat, in the transmission of Campylobacteriosis cannot be overstated. Antimicrobial resistance by Campylobacter spec...

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Main Authors: Nnabuife Bernard Agumah, Mustofa Helmi Effendi, Wiwiek Tyasningsih, Adiana Mutamsari Witaningrum, Emmanuel Nnabuike Ugbo, Onyinyechi Blessing Agumah, Riza Zainuddin Ahmad, Chinekwu Sherridan Nwagwu, Agatha Ifunanya Ugbo, Aswin Rafif Khairullah, Ikechukwu Benjamin Moses, Sheila Marty Yanestria, Katty Hendriana Priscilia Riwu, Wasito Wasito
Format: Article
Language:English
Published: Tripoli University 2025-04-01
Series:Open Veterinary Journal
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Online Access:http://www.ejmanager.com/fulltextpdf.php?mno=231143
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author Nnabuife Bernard Agumah
Mustofa Helmi Effendi
Wiwiek Tyasningsih
Adiana Mutamsari Witaningrum
Emmanuel Nnabuike Ugbo
Onyinyechi Blessing Agumah
Riza Zainuddin Ahmad
Chinekwu Sherridan Nwagwu
Agatha Ifunanya Ugbo
Aswin Rafif Khairullah
Ikechukwu Benjamin Moses
Sheila Marty Yanestria
Katty Hendriana Priscilia Riwu
Wasito Wasito
author_facet Nnabuife Bernard Agumah
Mustofa Helmi Effendi
Wiwiek Tyasningsih
Adiana Mutamsari Witaningrum
Emmanuel Nnabuike Ugbo
Onyinyechi Blessing Agumah
Riza Zainuddin Ahmad
Chinekwu Sherridan Nwagwu
Agatha Ifunanya Ugbo
Aswin Rafif Khairullah
Ikechukwu Benjamin Moses
Sheila Marty Yanestria
Katty Hendriana Priscilia Riwu
Wasito Wasito
author_sort Nnabuife Bernard Agumah
collection DOAJ
description Background: Campylobacter species have been at the forefront of the field as etiologic agents of foodborne gastroenteritis. The importance of animal proteins, especially contaminated meat, in the transmission of Campylobacteriosis cannot be overstated. Antimicrobial resistance by Campylobacter species is imminent, which underscores the importance of this study. Aim: This study aimed to determine the antibiograms of Campylobacter species isolated from various meat samples sold in Abakaliki to select Cephalosporin antibiotics. Methods: We purchased 100 samples of various meat, Chevon (25), Pork (25), Beef (25), and Chicken (25) from four different market locations in Abakaliki. Culture and bacterial isolation were aseptically performed using standard bacteriological techniques. Campylobacter isolates obtained were confirmed using standard biochemical tests. Antibiotic susceptibility was assessed using Kirby Bauer's disc diffusion method. The selected cephalosporins used in this study included cefoxitin, ceftriazone, and cefepime. Aztreonam was used as a tangential control. Results: Our results showed that 69.0% of Campylobacter coli was isolated from this study, with chickens having the highest distribution (92.0%). The isolation percentage of Campylobacter jejuni was 55.0%, with chicken also exhibiting the highest distribution (80.0%). The Ishieke market had the highest distribution of C. coli (75.0%). The central abattoir had the highest distribution for C. jejuni (50.0%). Resistance recorded by C. coli to various antibiotics employed include; Cefoxitin (52.2%), Ceftriazone (55.1%), Cefepime (57.9%), and azatreonam (73.9%). The resistance of C. jejuni to various antibiotics employed include; Cefoxitin (45.5%), Ceftriazone (60.0%), Cefepime (63.6%), and azatreonam (56.4%). Conclusion: The distribution of cephalosporin-resistant Campylobacter is high and represents a public health concern. More caution with hygiene and the use of antibiotics in animal husbandry is highly advocated. [Open Vet J 2025; 15(4.000): 1615-1623]
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issn 2226-4485
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publishDate 2025-04-01
publisher Tripoli University
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series Open Veterinary Journal
spelling doaj-art-76db342fd93240519ddf9ed9216232312025-08-20T03:09:38ZengTripoli UniversityOpen Veterinary Journal2226-44852218-60502025-04-011541615162310.5455/OVJ.2025.v15.i4.13231143Distribution of cephalosporin-resistant Campylobacter species isolated from meat sold in Abakaliki, NigeriaNnabuife Bernard Agumah0Mustofa Helmi Effendi1Wiwiek Tyasningsih2Adiana Mutamsari Witaningrum3Emmanuel Nnabuike Ugbo4Onyinyechi Blessing Agumah5Riza Zainuddin Ahmad6Chinekwu Sherridan Nwagwu7Agatha Ifunanya Ugbo8Aswin Rafif Khairullah9Ikechukwu Benjamin Moses10Sheila Marty Yanestria11Katty Hendriana Priscilia Riwu12Wasito Wasito13Department of Applied Microbiology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria Division of Veterinary Public Health, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia Division of Veterinary Microbiology, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia Division of Veterinary Public Health, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia Department of Applied Microbiology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria Department of Applied Microbiology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, West Java, Indonesia Department of Pharmaceutics, University of Nigeria, Obukpa Rd, Nsukka, Nigeria Department of Microbiology and Parasitology, David Umahi Federal University of Health Sciences, Uburu, Ebonyi state, Nigeria Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, West Java, Indonesia Department of Applied Microbiology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria Faculty of Veterinary Medicine, Universitas Wijaya Kusuma Surabaya, Surabaya, East Java, Indonesia Department of Veterinary Public Health, Faculty of Veterinary Medicine, Universitas Pendidikan Mandalika, Mataram, West Nusa Tenggara, Indonesia Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, West Java, IndonesiaBackground: Campylobacter species have been at the forefront of the field as etiologic agents of foodborne gastroenteritis. The importance of animal proteins, especially contaminated meat, in the transmission of Campylobacteriosis cannot be overstated. Antimicrobial resistance by Campylobacter species is imminent, which underscores the importance of this study. Aim: This study aimed to determine the antibiograms of Campylobacter species isolated from various meat samples sold in Abakaliki to select Cephalosporin antibiotics. Methods: We purchased 100 samples of various meat, Chevon (25), Pork (25), Beef (25), and Chicken (25) from four different market locations in Abakaliki. Culture and bacterial isolation were aseptically performed using standard bacteriological techniques. Campylobacter isolates obtained were confirmed using standard biochemical tests. Antibiotic susceptibility was assessed using Kirby Bauer's disc diffusion method. The selected cephalosporins used in this study included cefoxitin, ceftriazone, and cefepime. Aztreonam was used as a tangential control. Results: Our results showed that 69.0% of Campylobacter coli was isolated from this study, with chickens having the highest distribution (92.0%). The isolation percentage of Campylobacter jejuni was 55.0%, with chicken also exhibiting the highest distribution (80.0%). The Ishieke market had the highest distribution of C. coli (75.0%). The central abattoir had the highest distribution for C. jejuni (50.0%). Resistance recorded by C. coli to various antibiotics employed include; Cefoxitin (52.2%), Ceftriazone (55.1%), Cefepime (57.9%), and azatreonam (73.9%). The resistance of C. jejuni to various antibiotics employed include; Cefoxitin (45.5%), Ceftriazone (60.0%), Cefepime (63.6%), and azatreonam (56.4%). Conclusion: The distribution of cephalosporin-resistant Campylobacter is high and represents a public health concern. More caution with hygiene and the use of antibiotics in animal husbandry is highly advocated. [Open Vet J 2025; 15(4.000): 1615-1623]http://www.ejmanager.com/fulltextpdf.php?mno=231143campylobactercephalosporins-resistantmeatsnigeriapublic health
spellingShingle Nnabuife Bernard Agumah
Mustofa Helmi Effendi
Wiwiek Tyasningsih
Adiana Mutamsari Witaningrum
Emmanuel Nnabuike Ugbo
Onyinyechi Blessing Agumah
Riza Zainuddin Ahmad
Chinekwu Sherridan Nwagwu
Agatha Ifunanya Ugbo
Aswin Rafif Khairullah
Ikechukwu Benjamin Moses
Sheila Marty Yanestria
Katty Hendriana Priscilia Riwu
Wasito Wasito
Distribution of cephalosporin-resistant Campylobacter species isolated from meat sold in Abakaliki, Nigeria
Open Veterinary Journal
campylobacter
cephalosporins-resistant
meats
nigeria
public health
title Distribution of cephalosporin-resistant Campylobacter species isolated from meat sold in Abakaliki, Nigeria
title_full Distribution of cephalosporin-resistant Campylobacter species isolated from meat sold in Abakaliki, Nigeria
title_fullStr Distribution of cephalosporin-resistant Campylobacter species isolated from meat sold in Abakaliki, Nigeria
title_full_unstemmed Distribution of cephalosporin-resistant Campylobacter species isolated from meat sold in Abakaliki, Nigeria
title_short Distribution of cephalosporin-resistant Campylobacter species isolated from meat sold in Abakaliki, Nigeria
title_sort distribution of cephalosporin resistant campylobacter species isolated from meat sold in abakaliki nigeria
topic campylobacter
cephalosporins-resistant
meats
nigeria
public health
url http://www.ejmanager.com/fulltextpdf.php?mno=231143
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