Autologous precision-cut lung slice co-culture models for studying macrophage-driven fibrosis

Precision-cut lung slices (PCLS) are commonly used as an ex vivo model to study lung fibrosis; however, traditional models lack immune cell infiltration, including the recruitment of monocytes and macrophages, which are critical for inflammation and fibrosis. To address this limitation, we developed...

Full description

Saved in:
Bibliographic Details
Main Authors: So-Yi Chang, Wen-Hsin Chang, David C. Yang, Qi-Sheng Hong, Ssu-Wei Hsu, Reen Wu, Ching-Hsien Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1526787/full
Tags: Add Tag
No Tags, Be the first to tag this record!