Amphiphilic Poly(3-hydroxy alkanoate)s: Potential Candidates for Medical Applications

Poly(3-hydroxy alkanoate)s, PHAs, have been very attractive as biomaterials due to their biodegradability and biocompatibility. These hydrophobic natural polyesters, PHAs, need to have hydrophilic character particularly for drug delivery systems. In this manner, poly(ethylene glycol) (PEG) and hydro...

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Main Author: Baki Hazer
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2010/423460
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author Baki Hazer
author_facet Baki Hazer
author_sort Baki Hazer
collection DOAJ
description Poly(3-hydroxy alkanoate)s, PHAs, have been very attractive as biomaterials due to their biodegradability and biocompatibility. These hydrophobic natural polyesters, PHAs, need to have hydrophilic character particularly for drug delivery systems. In this manner, poly(ethylene glycol) (PEG) and hydrophilic functional groups such as amine, hydroxyl, carboxyl, and sulfonic acid have been introduced into the PHAs in order to obtain amphiphilic polymers. This review involves in the synthesis and characterization of the amphiphilic PHAs.
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spelling doaj-art-769fc47b8dd846158929eb32e6fdd90c2025-02-03T01:31:23ZengWileyInternational Journal of Polymer Science1687-94221687-94302010-01-01201010.1155/2010/423460423460Amphiphilic Poly(3-hydroxy alkanoate)s: Potential Candidates for Medical ApplicationsBaki Hazer0Department of Chemistry, Zonguldak Karaelmas University, 67100 Zonguldak, TurkeyPoly(3-hydroxy alkanoate)s, PHAs, have been very attractive as biomaterials due to their biodegradability and biocompatibility. These hydrophobic natural polyesters, PHAs, need to have hydrophilic character particularly for drug delivery systems. In this manner, poly(ethylene glycol) (PEG) and hydrophilic functional groups such as amine, hydroxyl, carboxyl, and sulfonic acid have been introduced into the PHAs in order to obtain amphiphilic polymers. This review involves in the synthesis and characterization of the amphiphilic PHAs.http://dx.doi.org/10.1155/2010/423460
spellingShingle Baki Hazer
Amphiphilic Poly(3-hydroxy alkanoate)s: Potential Candidates for Medical Applications
International Journal of Polymer Science
title Amphiphilic Poly(3-hydroxy alkanoate)s: Potential Candidates for Medical Applications
title_full Amphiphilic Poly(3-hydroxy alkanoate)s: Potential Candidates for Medical Applications
title_fullStr Amphiphilic Poly(3-hydroxy alkanoate)s: Potential Candidates for Medical Applications
title_full_unstemmed Amphiphilic Poly(3-hydroxy alkanoate)s: Potential Candidates for Medical Applications
title_short Amphiphilic Poly(3-hydroxy alkanoate)s: Potential Candidates for Medical Applications
title_sort amphiphilic poly 3 hydroxy alkanoate s potential candidates for medical applications
url http://dx.doi.org/10.1155/2010/423460
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