Amphiphilic Poly(3-hydroxy alkanoate)s: Potential Candidates for Medical Applications
Poly(3-hydroxy alkanoate)s, PHAs, have been very attractive as biomaterials due to their biodegradability and biocompatibility. These hydrophobic natural polyesters, PHAs, need to have hydrophilic character particularly for drug delivery systems. In this manner, poly(ethylene glycol) (PEG) and hydro...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
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| Series: | International Journal of Polymer Science |
| Online Access: | http://dx.doi.org/10.1155/2010/423460 |
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| Summary: | Poly(3-hydroxy alkanoate)s, PHAs, have been very attractive as biomaterials due to their biodegradability and biocompatibility. These hydrophobic natural polyesters, PHAs, need to have hydrophilic character particularly for drug delivery systems. In this manner, poly(ethylene glycol) (PEG) and hydrophilic functional groups such as amine, hydroxyl, carboxyl, and sulfonic acid have been introduced into the PHAs in order to obtain amphiphilic polymers. This review involves in the synthesis and characterization of the amphiphilic PHAs. |
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| ISSN: | 1687-9422 1687-9430 |