Extensive Longitudinal Transverse Myelitis Temporally Related to the Use of AZD1222, AstraZeneca COVID-19 Vaccine: Cerebrospinal Fluid Analysis and Recent Data Review

While mass immunization against coronavirus disease 2019 (COVID-19) rolls out around the globe, safety concerns and adverse events that need prompt evaluation are also emerging. Neurological complications such as transverse myelitis raise concerns as cases were observed in clinical trials. Cerebrosp...

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Main Authors: Paulo Diniz da Gama, Tiago Gomes de Alcantara, Rafaela Ramos Smaniotto, Penélope de Lima Petuco, Wammer Alves de Almeida, Rodrigo Assad Diiniz da Gama, Yara Dadalti Fragoso
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2022/8999853
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author Paulo Diniz da Gama
Tiago Gomes de Alcantara
Rafaela Ramos Smaniotto
Penélope de Lima Petuco
Wammer Alves de Almeida
Rodrigo Assad Diiniz da Gama
Yara Dadalti Fragoso
author_facet Paulo Diniz da Gama
Tiago Gomes de Alcantara
Rafaela Ramos Smaniotto
Penélope de Lima Petuco
Wammer Alves de Almeida
Rodrigo Assad Diiniz da Gama
Yara Dadalti Fragoso
author_sort Paulo Diniz da Gama
collection DOAJ
description While mass immunization against coronavirus disease 2019 (COVID-19) rolls out around the globe, safety concerns and adverse events that need prompt evaluation are also emerging. Neurological complications such as transverse myelitis raise concerns as cases were observed in clinical trials. Cerebrospinal fluid analysis is routine in these cases and the characteristics of the abnormalities found are of great help not only in establishing the diagnosis but also in understanding this rare condition. We present a case of extensive longitudinal transverse myelitis after vaccination with AZD1222, AstraZeneca COVID-19 vaccine, which was the first case reported in Brazil. The abnormalities found in the study of the cerebrospinal fluid in our case are reported and discussed using data from recent publications.
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institution Kabale University
issn 2090-6676
language English
publishDate 2022-01-01
publisher Wiley
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series Case Reports in Neurological Medicine
spelling doaj-art-769d223e7e544d379d7037487b2a47762025-02-03T01:07:22ZengWileyCase Reports in Neurological Medicine2090-66762022-01-01202210.1155/2022/8999853Extensive Longitudinal Transverse Myelitis Temporally Related to the Use of AZD1222, AstraZeneca COVID-19 Vaccine: Cerebrospinal Fluid Analysis and Recent Data ReviewPaulo Diniz da Gama0Tiago Gomes de Alcantara1Rafaela Ramos Smaniotto2Penélope de Lima Petuco3Wammer Alves de Almeida4Rodrigo Assad Diiniz da Gama5Yara Dadalti Fragoso6Faculty of Medical Sciences of SorocabaThe Conjunto Hospitalar de SorocabaFaculty of Medical Sciences of SorocabaFaculty of Medical Sciences of SorocabaFaculty of Medical Sciences of SorocabaThe Conjunto Hospitalar de SorocabaUniversidade Metropolitana de SantosWhile mass immunization against coronavirus disease 2019 (COVID-19) rolls out around the globe, safety concerns and adverse events that need prompt evaluation are also emerging. Neurological complications such as transverse myelitis raise concerns as cases were observed in clinical trials. Cerebrospinal fluid analysis is routine in these cases and the characteristics of the abnormalities found are of great help not only in establishing the diagnosis but also in understanding this rare condition. We present a case of extensive longitudinal transverse myelitis after vaccination with AZD1222, AstraZeneca COVID-19 vaccine, which was the first case reported in Brazil. The abnormalities found in the study of the cerebrospinal fluid in our case are reported and discussed using data from recent publications.http://dx.doi.org/10.1155/2022/8999853
spellingShingle Paulo Diniz da Gama
Tiago Gomes de Alcantara
Rafaela Ramos Smaniotto
Penélope de Lima Petuco
Wammer Alves de Almeida
Rodrigo Assad Diiniz da Gama
Yara Dadalti Fragoso
Extensive Longitudinal Transverse Myelitis Temporally Related to the Use of AZD1222, AstraZeneca COVID-19 Vaccine: Cerebrospinal Fluid Analysis and Recent Data Review
Case Reports in Neurological Medicine
title Extensive Longitudinal Transverse Myelitis Temporally Related to the Use of AZD1222, AstraZeneca COVID-19 Vaccine: Cerebrospinal Fluid Analysis and Recent Data Review
title_full Extensive Longitudinal Transverse Myelitis Temporally Related to the Use of AZD1222, AstraZeneca COVID-19 Vaccine: Cerebrospinal Fluid Analysis and Recent Data Review
title_fullStr Extensive Longitudinal Transverse Myelitis Temporally Related to the Use of AZD1222, AstraZeneca COVID-19 Vaccine: Cerebrospinal Fluid Analysis and Recent Data Review
title_full_unstemmed Extensive Longitudinal Transverse Myelitis Temporally Related to the Use of AZD1222, AstraZeneca COVID-19 Vaccine: Cerebrospinal Fluid Analysis and Recent Data Review
title_short Extensive Longitudinal Transverse Myelitis Temporally Related to the Use of AZD1222, AstraZeneca COVID-19 Vaccine: Cerebrospinal Fluid Analysis and Recent Data Review
title_sort extensive longitudinal transverse myelitis temporally related to the use of azd1222 astrazeneca covid 19 vaccine cerebrospinal fluid analysis and recent data review
url http://dx.doi.org/10.1155/2022/8999853
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