Identification of a novel mechanism for regulation of the early autophagy machinery assembly by PKA
The E3-like complex Atg12-Atg5-Atg16, which promotes Atg8 lipidation, is recruited to the autophagosomal membrane through the interaction of Atg16 with the PROPPIN/WIPI protein Atg21, as well as by the binding of Atg12 to Atg17, the scaffold protein of the Atg1 kinase complex in yeast. In order to g...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
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| Series: | Autophagy Reports |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/27694127.2025.2503226 |
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