Lifestyle Factors in Hypertension Drug Research: Systematic Analysis of Articles in a Leading Cochrane Report
Established standards for first-line hypertension management include lifestyle modification and behavior change. The degree to which and how lifestyle modification is systematically integrated into studies of first-line drug management for hypertension is of methodological and clinical relevance. Th...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2014/835716 |
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| _version_ | 1832550080197951488 |
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| author | Dan E. Wilson Tashina Van Vlack Brendin P. Schievink Eric B. Doak Jason S. Shane Elizabeth Dean |
| author_facet | Dan E. Wilson Tashina Van Vlack Brendin P. Schievink Eric B. Doak Jason S. Shane Elizabeth Dean |
| author_sort | Dan E. Wilson |
| collection | DOAJ |
| description | Established standards for first-line hypertension management include lifestyle modification and behavior change. The degree to which and how lifestyle modification is systematically integrated into studies of first-line drug management for hypertension is of methodological and clinical relevance. This study systematically reviewed the methodology of articles from a recent Cochrane review that had been designed to inform first-line medical treatment of hypertension and was representative of high quality established clinical trials in the field. Source articles (n=34) were systematically reviewed for lifestyle interventions including smoking cessation, diet, weight loss, physical activity and exercise, stress reduction, and moderate alcohol consumption. 54% of articles did not mention lifestyle modification; 46% contained nonspecific descriptions of interventions. We contend that hypertension management research trials (including drug studies) need to elucidate the benefits and risks of drug-lifestyle interaction, to support the priority of lifestyle modification, and that lifestyle modification, rather than drugs, is seen by patients and the public as a priority for health professionals. The inclusion of lifestyle modification strategies in research designs for hypertension drug trials could enhance current research, from trial efficacy to clinical outcome effectiveness, and align hypertension best practices of a range of health professionals with evidence-based knowledge translation. |
| format | Article |
| id | doaj-art-7658f60c106d4f9c95bc184d46746e1d |
| institution | Kabale University |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-7658f60c106d4f9c95bc184d46746e1d2025-02-03T06:07:44ZengWileyInternational Journal of Hypertension2090-03842090-03922014-01-01201410.1155/2014/835716835716Lifestyle Factors in Hypertension Drug Research: Systematic Analysis of Articles in a Leading Cochrane ReportDan E. Wilson0Tashina Van Vlack1Brendin P. Schievink2Eric B. Doak3Jason S. Shane4Elizabeth Dean5Allan McGavin Sports Medicine Centre, University of British Columbia, Vancouver, BC, V6T 1Z3, CanadaFather David Bauer Clinic (Centric Health Corporation), Calgary, AB, T2N 3Y9, CanadaCBI Health Centre, Duncan, BC, V9L 1N8, CanadaSquamish Physio & Wellness Centre, Squamish, BC, V8B 0B4, CanadaMovéo Sport and Rehabilitation Centre, North Vancouver, BC, V7L 2P7, CanadaDepartment of Physical Therapy, Faculty of Medicine, University of BC, Vancouver, BC, V6T 1Z3, CanadaEstablished standards for first-line hypertension management include lifestyle modification and behavior change. The degree to which and how lifestyle modification is systematically integrated into studies of first-line drug management for hypertension is of methodological and clinical relevance. This study systematically reviewed the methodology of articles from a recent Cochrane review that had been designed to inform first-line medical treatment of hypertension and was representative of high quality established clinical trials in the field. Source articles (n=34) were systematically reviewed for lifestyle interventions including smoking cessation, diet, weight loss, physical activity and exercise, stress reduction, and moderate alcohol consumption. 54% of articles did not mention lifestyle modification; 46% contained nonspecific descriptions of interventions. We contend that hypertension management research trials (including drug studies) need to elucidate the benefits and risks of drug-lifestyle interaction, to support the priority of lifestyle modification, and that lifestyle modification, rather than drugs, is seen by patients and the public as a priority for health professionals. The inclusion of lifestyle modification strategies in research designs for hypertension drug trials could enhance current research, from trial efficacy to clinical outcome effectiveness, and align hypertension best practices of a range of health professionals with evidence-based knowledge translation.http://dx.doi.org/10.1155/2014/835716 |
| spellingShingle | Dan E. Wilson Tashina Van Vlack Brendin P. Schievink Eric B. Doak Jason S. Shane Elizabeth Dean Lifestyle Factors in Hypertension Drug Research: Systematic Analysis of Articles in a Leading Cochrane Report International Journal of Hypertension |
| title | Lifestyle Factors in Hypertension Drug Research: Systematic Analysis of Articles in a Leading Cochrane Report |
| title_full | Lifestyle Factors in Hypertension Drug Research: Systematic Analysis of Articles in a Leading Cochrane Report |
| title_fullStr | Lifestyle Factors in Hypertension Drug Research: Systematic Analysis of Articles in a Leading Cochrane Report |
| title_full_unstemmed | Lifestyle Factors in Hypertension Drug Research: Systematic Analysis of Articles in a Leading Cochrane Report |
| title_short | Lifestyle Factors in Hypertension Drug Research: Systematic Analysis of Articles in a Leading Cochrane Report |
| title_sort | lifestyle factors in hypertension drug research systematic analysis of articles in a leading cochrane report |
| url | http://dx.doi.org/10.1155/2014/835716 |
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