Navigating the potential and pitfalls of large language models in patient-centered medication guidance and self-decision support

Large Language Models (LLMs) are transforming patient education in medication management by providing accessible information to support healthcare decision-making. Building on our recent scoping review of LLMs in patient education, this perspective examines their specific role in medication guidance...

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Main Authors: Serhat Aydin, Mert Karabacak, Victoria Vlachos, Konstantinos Margetis
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1527864/full
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author Serhat Aydin
Mert Karabacak
Victoria Vlachos
Konstantinos Margetis
author_facet Serhat Aydin
Mert Karabacak
Victoria Vlachos
Konstantinos Margetis
author_sort Serhat Aydin
collection DOAJ
description Large Language Models (LLMs) are transforming patient education in medication management by providing accessible information to support healthcare decision-making. Building on our recent scoping review of LLMs in patient education, this perspective examines their specific role in medication guidance. These artificial intelligence (AI)-driven tools can generate comprehensive responses about drug interactions, side effects, and emergency care protocols, potentially enhancing patient autonomy in medication decisions. However, significant challenges exist, including the risk of misinformation and the complexity of providing accurate drug information without access to individual patient data. Safety concerns are particularly acute when patients rely solely on AI-generated advice for self-medication decisions. This perspective analyzes current capabilities, examines critical limitations, and raises questions regarding the possible integration of LLMs in medication guidance. We emphasize the need for regulatory oversight to ensure these tools serve as supplements to, rather than replacements for, professional healthcare guidance.
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issn 2296-858X
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spelling doaj-art-7652f74836b1471791a951df716ca3992025-01-23T06:56:18ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-01-011210.3389/fmed.2025.15278641527864Navigating the potential and pitfalls of large language models in patient-centered medication guidance and self-decision supportSerhat Aydin0Mert Karabacak1Victoria Vlachos2Konstantinos Margetis3School of Medicine, Koç University, Istanbul, TürkiyeDepartment of Neurosurgery, Mount Sinai Health System, New York, NY, United StatesCollege of Human Ecology, Cornell University, Ithaca, NY, United StatesDepartment of Neurosurgery, Mount Sinai Health System, New York, NY, United StatesLarge Language Models (LLMs) are transforming patient education in medication management by providing accessible information to support healthcare decision-making. Building on our recent scoping review of LLMs in patient education, this perspective examines their specific role in medication guidance. These artificial intelligence (AI)-driven tools can generate comprehensive responses about drug interactions, side effects, and emergency care protocols, potentially enhancing patient autonomy in medication decisions. However, significant challenges exist, including the risk of misinformation and the complexity of providing accurate drug information without access to individual patient data. Safety concerns are particularly acute when patients rely solely on AI-generated advice for self-medication decisions. This perspective analyzes current capabilities, examines critical limitations, and raises questions regarding the possible integration of LLMs in medication guidance. We emphasize the need for regulatory oversight to ensure these tools serve as supplements to, rather than replacements for, professional healthcare guidance.https://www.frontiersin.org/articles/10.3389/fmed.2025.1527864/fullLarge Language ModelsChatGPTpatient educationself-medicationartificial intelligencemachine learning
spellingShingle Serhat Aydin
Mert Karabacak
Victoria Vlachos
Konstantinos Margetis
Navigating the potential and pitfalls of large language models in patient-centered medication guidance and self-decision support
Frontiers in Medicine
Large Language Models
ChatGPT
patient education
self-medication
artificial intelligence
machine learning
title Navigating the potential and pitfalls of large language models in patient-centered medication guidance and self-decision support
title_full Navigating the potential and pitfalls of large language models in patient-centered medication guidance and self-decision support
title_fullStr Navigating the potential and pitfalls of large language models in patient-centered medication guidance and self-decision support
title_full_unstemmed Navigating the potential and pitfalls of large language models in patient-centered medication guidance and self-decision support
title_short Navigating the potential and pitfalls of large language models in patient-centered medication guidance and self-decision support
title_sort navigating the potential and pitfalls of large language models in patient centered medication guidance and self decision support
topic Large Language Models
ChatGPT
patient education
self-medication
artificial intelligence
machine learning
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1527864/full
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