Research on Red/Near-Infrared Fluorescent Carbon Dots Based on Different Carbon Sources and Solvents: Fluorescence Mechanism and Biological Applications

Fluorescent carbon dots, especially red/near-infrared-emitting CDs, are becoming increasingly important in the field of biomedicine. This article reviews the synthesis, fluorescence mechanisms, and biological applications of R/NIR-CDs, emphasizing the importance of carbon source and solvent selectio...

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Main Authors: Jun Song, Minghao Kang, Shujian Ji, Shuai Ye, Jiaqing Guo
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/15/2/81
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author Jun Song
Minghao Kang
Shujian Ji
Shuai Ye
Jiaqing Guo
author_facet Jun Song
Minghao Kang
Shujian Ji
Shuai Ye
Jiaqing Guo
author_sort Jun Song
collection DOAJ
description Fluorescent carbon dots, especially red/near-infrared-emitting CDs, are becoming increasingly important in the field of biomedicine. This article reviews the synthesis, fluorescence mechanisms, and biological applications of R/NIR-CDs, emphasizing the importance of carbon source and solvent selection in controlling their optical properties. The formation process of CDs is classified, and the fluorescence mechanisms of CDs are summarized, involving carbon core states, surface states, molecular states, and cross-linking enhanced emission effects. This article also highlights the applications of R/NIR-CDs in bioimaging, biosensing, phototherapy, and drug delivery. The final section discusses challenges and prospects.
format Article
id doaj-art-762bd4771bd94c5d9ecace8eabeb5508
institution Kabale University
issn 2079-4991
language English
publishDate 2025-01-01
publisher MDPI AG
record_format Article
series Nanomaterials
spelling doaj-art-762bd4771bd94c5d9ecace8eabeb55082025-01-24T13:44:04ZengMDPI AGNanomaterials2079-49912025-01-011528110.3390/nano15020081Research on Red/Near-Infrared Fluorescent Carbon Dots Based on Different Carbon Sources and Solvents: Fluorescence Mechanism and Biological ApplicationsJun Song0Minghao Kang1Shujian Ji2Shuai Ye3Jiaqing Guo4State Key Laboratory of Radio Frequency Heterogeneous Integration, College of Physics and Optoelectronic Engineering, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Shenzhen University, Shenzhen 518060, ChinaState Key Laboratory of Radio Frequency Heterogeneous Integration, College of Physics and Optoelectronic Engineering, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Shenzhen University, Shenzhen 518060, ChinaState Key Laboratory of Radio Frequency Heterogeneous Integration, College of Physics and Optoelectronic Engineering, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Shenzhen University, Shenzhen 518060, ChinaState Key Laboratory of Radio Frequency Heterogeneous Integration, College of Physics and Optoelectronic Engineering, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Shenzhen University, Shenzhen 518060, ChinaState Key Laboratory of Radio Frequency Heterogeneous Integration, College of Physics and Optoelectronic Engineering, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, Shenzhen University, Shenzhen 518060, ChinaFluorescent carbon dots, especially red/near-infrared-emitting CDs, are becoming increasingly important in the field of biomedicine. This article reviews the synthesis, fluorescence mechanisms, and biological applications of R/NIR-CDs, emphasizing the importance of carbon source and solvent selection in controlling their optical properties. The formation process of CDs is classified, and the fluorescence mechanisms of CDs are summarized, involving carbon core states, surface states, molecular states, and cross-linking enhanced emission effects. This article also highlights the applications of R/NIR-CDs in bioimaging, biosensing, phototherapy, and drug delivery. The final section discusses challenges and prospects.https://www.mdpi.com/2079-4991/15/2/81R/NIR-CDsbiological applicationsfluorescence mechanismssynthesisoptical properties
spellingShingle Jun Song
Minghao Kang
Shujian Ji
Shuai Ye
Jiaqing Guo
Research on Red/Near-Infrared Fluorescent Carbon Dots Based on Different Carbon Sources and Solvents: Fluorescence Mechanism and Biological Applications
Nanomaterials
R/NIR-CDs
biological applications
fluorescence mechanisms
synthesis
optical properties
title Research on Red/Near-Infrared Fluorescent Carbon Dots Based on Different Carbon Sources and Solvents: Fluorescence Mechanism and Biological Applications
title_full Research on Red/Near-Infrared Fluorescent Carbon Dots Based on Different Carbon Sources and Solvents: Fluorescence Mechanism and Biological Applications
title_fullStr Research on Red/Near-Infrared Fluorescent Carbon Dots Based on Different Carbon Sources and Solvents: Fluorescence Mechanism and Biological Applications
title_full_unstemmed Research on Red/Near-Infrared Fluorescent Carbon Dots Based on Different Carbon Sources and Solvents: Fluorescence Mechanism and Biological Applications
title_short Research on Red/Near-Infrared Fluorescent Carbon Dots Based on Different Carbon Sources and Solvents: Fluorescence Mechanism and Biological Applications
title_sort research on red near infrared fluorescent carbon dots based on different carbon sources and solvents fluorescence mechanism and biological applications
topic R/NIR-CDs
biological applications
fluorescence mechanisms
synthesis
optical properties
url https://www.mdpi.com/2079-4991/15/2/81
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AT shujianji researchonrednearinfraredfluorescentcarbondotsbasedondifferentcarbonsourcesandsolventsfluorescencemechanismandbiologicalapplications
AT shuaiye researchonrednearinfraredfluorescentcarbondotsbasedondifferentcarbonsourcesandsolventsfluorescencemechanismandbiologicalapplications
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