An Adverse Reaction in the Pediatric Sleep Laboratory
We present a case of a 15-month-old boy with Cornelia de Lange Syndrome (NIPBL gene mutation). On a PSG, central sleep apnea (central apnea-hypopnea index of 19/hour) and nocturnal hypoventilation (transcutaneous CO2 > 50 mmHg for 53% of the night) were found. A positive pressure initiation study...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2016/9712579 |
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| author | Diana Reppucci Debra Medin Suhail Al-Saleh Mary Jane Smith Jill Barter Reshma Amin |
| author_facet | Diana Reppucci Debra Medin Suhail Al-Saleh Mary Jane Smith Jill Barter Reshma Amin |
| author_sort | Diana Reppucci |
| collection | DOAJ |
| description | We present a case of a 15-month-old boy with Cornelia de Lange Syndrome (NIPBL gene mutation). On a PSG, central sleep apnea (central apnea-hypopnea index of 19/hour) and nocturnal hypoventilation (transcutaneous CO2 > 50 mmHg for 53% of the night) were found. A positive pressure initiation study was aborted because the patient developed a serious adverse reaction. The differential diagnosis included a skin fragility condition versus an allergic contact dermatitis to the interface; this could be from the povidone-iodine solution used to clean the NiPPV interface or from the plastic of the interface itself. A skin biopsy was performed which was normal. The reaction was likely secondary to an allergic contact dermatitis from the povidone-iodine solution used to clean the NiPPV interface. The patient is currently tolerating NiPPV. |
| format | Article |
| id | doaj-art-7623fcae3e9145e98ec1ea6c21d61a86 |
| institution | Kabale University |
| issn | 1198-2241 1916-7245 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-7623fcae3e9145e98ec1ea6c21d61a862025-02-03T01:30:30ZengWileyCanadian Respiratory Journal1198-22411916-72452016-01-01201610.1155/2016/97125799712579An Adverse Reaction in the Pediatric Sleep LaboratoryDiana Reppucci0Debra Medin1Suhail Al-Saleh2Mary Jane Smith3Jill Barter4Reshma Amin5Division of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, M5G IX8, CanadaDivision of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, M5G IX8, CanadaDivision of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, M5G IX8, CanadaJaneway Children’s Health and Rehabilitation Centre, St. John’s, NL, A1B 3V6, CanadaJaneway Children’s Health and Rehabilitation Centre, St. John’s, NL, A1B 3V6, CanadaDivision of Respiratory Medicine, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, M5G IX8, CanadaWe present a case of a 15-month-old boy with Cornelia de Lange Syndrome (NIPBL gene mutation). On a PSG, central sleep apnea (central apnea-hypopnea index of 19/hour) and nocturnal hypoventilation (transcutaneous CO2 > 50 mmHg for 53% of the night) were found. A positive pressure initiation study was aborted because the patient developed a serious adverse reaction. The differential diagnosis included a skin fragility condition versus an allergic contact dermatitis to the interface; this could be from the povidone-iodine solution used to clean the NiPPV interface or from the plastic of the interface itself. A skin biopsy was performed which was normal. The reaction was likely secondary to an allergic contact dermatitis from the povidone-iodine solution used to clean the NiPPV interface. The patient is currently tolerating NiPPV.http://dx.doi.org/10.1155/2016/9712579 |
| spellingShingle | Diana Reppucci Debra Medin Suhail Al-Saleh Mary Jane Smith Jill Barter Reshma Amin An Adverse Reaction in the Pediatric Sleep Laboratory Canadian Respiratory Journal |
| title | An Adverse Reaction in the Pediatric Sleep Laboratory |
| title_full | An Adverse Reaction in the Pediatric Sleep Laboratory |
| title_fullStr | An Adverse Reaction in the Pediatric Sleep Laboratory |
| title_full_unstemmed | An Adverse Reaction in the Pediatric Sleep Laboratory |
| title_short | An Adverse Reaction in the Pediatric Sleep Laboratory |
| title_sort | adverse reaction in the pediatric sleep laboratory |
| url | http://dx.doi.org/10.1155/2016/9712579 |
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