Innate Immunity and Neuroinflammation
Inflammation of central nervous system (CNS) is usually associated with trauma and infection. Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2013/342931 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832562881444446208 |
|---|---|
| author | Abhishek Shastri Domenico Marco Bonifati Uday Kishore |
| author_facet | Abhishek Shastri Domenico Marco Bonifati Uday Kishore |
| author_sort | Abhishek Shastri |
| collection | DOAJ |
| description | Inflammation of central nervous system (CNS) is usually associated with trauma and infection. Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful. Innate immune system consisting of pattern-recognition receptors, macrophages, and complement system plays a key role in CNS homeostasis following injury and infection. Here, we discuss how innate immune components can also contribute to neuroinflammation and neurodegeneration. |
| format | Article |
| id | doaj-art-7616e96819fb4ab28b6df7a495023b2f |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-7616e96819fb4ab28b6df7a495023b2f2025-02-03T01:21:36ZengWileyMediators of Inflammation0962-93511466-18612013-01-01201310.1155/2013/342931342931Innate Immunity and NeuroinflammationAbhishek Shastri0Domenico Marco Bonifati1Uday Kishore2Centre for Infection, Immunity and Disease Mechanisms, Heinz Wolff Building, Brunel University, London UB8 3PH, UKUnit of Neurology, Department of Neurological Disorders, Santa Chiara Hospital, Largo Medaglie d'oro 1, 38100 Trento, ItalyCentre for Infection, Immunity and Disease Mechanisms, Heinz Wolff Building, Brunel University, London UB8 3PH, UKInflammation of central nervous system (CNS) is usually associated with trauma and infection. Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful. Innate immune system consisting of pattern-recognition receptors, macrophages, and complement system plays a key role in CNS homeostasis following injury and infection. Here, we discuss how innate immune components can also contribute to neuroinflammation and neurodegeneration.http://dx.doi.org/10.1155/2013/342931 |
| spellingShingle | Abhishek Shastri Domenico Marco Bonifati Uday Kishore Innate Immunity and Neuroinflammation Mediators of Inflammation |
| title | Innate Immunity and Neuroinflammation |
| title_full | Innate Immunity and Neuroinflammation |
| title_fullStr | Innate Immunity and Neuroinflammation |
| title_full_unstemmed | Innate Immunity and Neuroinflammation |
| title_short | Innate Immunity and Neuroinflammation |
| title_sort | innate immunity and neuroinflammation |
| url | http://dx.doi.org/10.1155/2013/342931 |
| work_keys_str_mv | AT abhishekshastri innateimmunityandneuroinflammation AT domenicomarcobonifati innateimmunityandneuroinflammation AT udaykishore innateimmunityandneuroinflammation |