Intracranial artery dolichoectasia: What should the neurologist know?
Intracranial artery dolichoectasia (IADE) is a vascular anomaly characterized by dilation and/or tortuosity of one or more intracranial arteries. While many cases are incidental findings on imaging, the associated ischemic neurological complications of IADE can be severe and must be promptly recogni...
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| Format: | Article |
| Language: | English |
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Open Exploration Publishing Inc.
2025-01-01
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| Series: | Exploration of Neuroscience |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A100671/100671.pdf |
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| _version_ | 1832586134847225856 |
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| author | Lorena Dellagnesi Depieri Renan Rodrigues Neves Ribeiro do Nascimento Lorena Souza Viana |
| author_facet | Lorena Dellagnesi Depieri Renan Rodrigues Neves Ribeiro do Nascimento Lorena Souza Viana |
| author_sort | Lorena Dellagnesi Depieri |
| collection | DOAJ |
| description | Intracranial artery dolichoectasia (IADE) is a vascular anomaly characterized by dilation and/or tortuosity of one or more intracranial arteries. While many cases are incidental findings on imaging, the associated ischemic neurological complications of IADE can be severe and must be promptly recognized. This study aims to increase awareness among general practitioners and neurologists regarding this rare and potentially life-threatening condition. We utilized reputable databases for this scoping review, including PubMed, Scopus, and Google Scholar, from database inception through September 2024, using a combination of terms such as “Dolichoectasia of Basilar Artery”, “Intracranial Dolichoectasia”, and “Ischemic Stroke”. Our scoping review revealed that IADE is a challenging and often underdiagnosed condition, with an estimated prevalence of less than 1% in the general population. Hypertension, atherosclerosis, and advanced age are well-documented risk factors. To minimize the risk of misdiagnosis, we briefly elucidated the pathophysiology of IADE, correlating it with clinical and radiological features. We discuss the diagnostic criteria for IADE based on radiological imaging, addressing the advantages and limitations of different techniques. Finally, we highlight the unmet clinical needs related to IADE management, which may involve pharmacological and surgical therapies tailored to individual cases, with careful consideration of safety and efficacy. |
| format | Article |
| id | doaj-art-75c9dc1bc6744511a50ad3ef33f929ec |
| institution | Kabale University |
| issn | 2834-5347 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Open Exploration Publishing Inc. |
| record_format | Article |
| series | Exploration of Neuroscience |
| spelling | doaj-art-75c9dc1bc6744511a50ad3ef33f929ec2025-01-26T08:32:27ZengOpen Exploration Publishing Inc.Exploration of Neuroscience2834-53472025-01-01410067110.37349/en.2025.100671Intracranial artery dolichoectasia: What should the neurologist know?Lorena Dellagnesi Depieri0https://orcid.org/0000-0002-4141-0597Renan Rodrigues Neves Ribeiro do Nascimento1https://orcid.org/0000-0002-2638-0086Lorena Souza Viana2https://orcid.org/0000-0002-0141-5174Centro Universitário Faculdade Das Américas, São Paulo 01304-001, BrazilDepartamento de Reumatologia, Universidade Federal de São Paulo, São Paulo 04039-050, BrazilDepartamento de Neurologia e Pacientes Graves, Hospital Israelita Albert Einstein, São Paulo 05652-900, Brazil; Departamento de Neurologia, Hospital das Clínicas da Faculdade de Medicina, Universidade de São Paulo, São Paulo 05403-010, BrazilIntracranial artery dolichoectasia (IADE) is a vascular anomaly characterized by dilation and/or tortuosity of one or more intracranial arteries. While many cases are incidental findings on imaging, the associated ischemic neurological complications of IADE can be severe and must be promptly recognized. This study aims to increase awareness among general practitioners and neurologists regarding this rare and potentially life-threatening condition. We utilized reputable databases for this scoping review, including PubMed, Scopus, and Google Scholar, from database inception through September 2024, using a combination of terms such as “Dolichoectasia of Basilar Artery”, “Intracranial Dolichoectasia”, and “Ischemic Stroke”. Our scoping review revealed that IADE is a challenging and often underdiagnosed condition, with an estimated prevalence of less than 1% in the general population. Hypertension, atherosclerosis, and advanced age are well-documented risk factors. To minimize the risk of misdiagnosis, we briefly elucidated the pathophysiology of IADE, correlating it with clinical and radiological features. We discuss the diagnostic criteria for IADE based on radiological imaging, addressing the advantages and limitations of different techniques. Finally, we highlight the unmet clinical needs related to IADE management, which may involve pharmacological and surgical therapies tailored to individual cases, with careful consideration of safety and efficacy.https://www.explorationpub.com/uploads/Article/A100671/100671.pdfdolichoectasiaintracranial aneurysmbasilar arterycerebrovascular disordersvascular malformationsstroke |
| spellingShingle | Lorena Dellagnesi Depieri Renan Rodrigues Neves Ribeiro do Nascimento Lorena Souza Viana Intracranial artery dolichoectasia: What should the neurologist know? Exploration of Neuroscience dolichoectasia intracranial aneurysm basilar artery cerebrovascular disorders vascular malformations stroke |
| title | Intracranial artery dolichoectasia: What should the neurologist know? |
| title_full | Intracranial artery dolichoectasia: What should the neurologist know? |
| title_fullStr | Intracranial artery dolichoectasia: What should the neurologist know? |
| title_full_unstemmed | Intracranial artery dolichoectasia: What should the neurologist know? |
| title_short | Intracranial artery dolichoectasia: What should the neurologist know? |
| title_sort | intracranial artery dolichoectasia what should the neurologist know |
| topic | dolichoectasia intracranial aneurysm basilar artery cerebrovascular disorders vascular malformations stroke |
| url | https://www.explorationpub.com/uploads/Article/A100671/100671.pdf |
| work_keys_str_mv | AT lorenadellagnesidepieri intracranialarterydolichoectasiawhatshouldtheneurologistknow AT renanrodriguesnevesribeirodonascimento intracranialarterydolichoectasiawhatshouldtheneurologistknow AT lorenasouzaviana intracranialarterydolichoectasiawhatshouldtheneurologistknow |